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- W2499684430 endingPage "445" @default.
- W2499684430 startingPage "405" @default.
- W2499684430 abstract "This chapter discusses the preventive measures that can reduce the risk of bone disease in candidates of organ transplant. In a high proportion of organ transplant recipients, metabolic abnormalities overwhelm the ability of the bone to respond to stress, which results in structural failure and fractures. Transplant recipients who don't appear to have many risk factors may nevertheless experience fractures, and those who do have “traditional” risk factors have an even greater chance of suffering from a fracture. Therefore, it is important to check these patients for both major and minor risk factors, and to correct those that are amenable to treatment. Because it is easier to prevent bone loss than it is to restore bone, optimization of factors that relate to bone health should be done as soon as possible. Transplant candidates frequently have multiple risk factors for bone fragility. These complex patients present a challenge to their physicians. In addition to the risk factors defined by epidemiological studies of the general population, the transplant candidates have risk factors depending on which organ has failed. Therapeutic choices may be limited or ineffective, and side effects may be more pronounced. Definitive studies on the benefits of preventive treatment in transplant candidates are lacking. Attention to all the cumulative risk factors and treatment within the available options will hopefully result in stronger bones with fewer fractures." @default.
- W2499684430 created "2016-08-23" @default.
- W2499684430 creator A5011577039 @default.
- W2499684430 date "2005-01-01" @default.
- W2499684430 modified "2023-09-27" @default.
- W2499684430 title "Management of Bone Disease in Candidates for Organ Transplant" @default.
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