FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2499695817> ?p ?o ?g. }

• W2499695817 endingPage "76" @default.
• W2499695817 startingPage "69" @default.
• W2499695817 abstract "Different infusion rates of doxorubicin (DOX) have been used for treating human malignancies. Organ toxicity after DOX infusion is a major issue in treatment disruption. However, whether different DOX infusion rates induce different toxicity is still unknown. In this study, we examined the toxicity effects of different DOX infusion rates in the early phase of organ toxicity. Thirty-six rats were randomly divided into 5-, 15-, and 30-min infusion rate groups. A single dose of DOX (8.3 mg/kg, I.V.) was administered at different infusion rates. Blood samples were collected from the femoral artery at 1, 3, 6, 9, 12, 18, 24, 36, and 48 h after DOX administration. The blood cell count and blood biochemistry were analyzed. The liver, kidney, and heart were removed for pathological examinations after the rats were sacrificed. Our findings show that the 30-min group had higher injury markers in the liver (glutamic oxaloacetic transaminase and glutamic pyruvic transaminase), kidneys (blood urea nitrogen and creatinine), and heart (creatine phosphokinase-MB and lactate dehydrogenase), and had higher tumor necrosis factor-alpha and interleukin 6 levels than did the other groups. The 30-min group also had more severe damage according to the pathological examinations. In conclusion, slower infusion of DOX induced a higher inflammatory response and greater organ damage." @default.
• W2499695817 created "2016-08-23" @default.
• W2499695817 creator A5021828244 @default.
• W2499695817 creator A5033984384 @default.
• W2499695817 creator A5038957478 @default.
• W2499695817 creator A5067684050 @default.
• W2499695817 creator A5071850550 @default.
• W2499695817 date "2016-11-01" @default.
• W2499695817 modified "2023-10-13" @default.
• W2499695817 title "Slow infusion rate of doxorubicin induces higher pro-inflammatory cytokine production" @default.
• W2499695817 cites W1518840278 @default.
• W2499695817 cites W1549139000 @default.
• W2499695817 cites W1963578253 @default.
• W2499695817 cites W1965688832 @default.
• W2499695817 cites W1973414672 @default.
• W2499695817 cites W1976051281 @default.
• W2499695817 cites W1980502996 @default.
• W2499695817 cites W1986840659 @default.
• W2499695817 cites W2009337734 @default.
• W2499695817 cites W2010183849 @default.
• W2499695817 cites W2023505415 @default.
• W2499695817 cites W2025639667 @default.
• W2499695817 cites W2026392526 @default.
• W2499695817 cites W2043276558 @default.
• W2499695817 cites W2056842005 @default.
• W2499695817 cites W2062662242 @default.
• W2499695817 cites W2079109822 @default.
• W2499695817 cites W2089357150 @default.
• W2499695817 cites W2094156804 @default.
• W2499695817 cites W2098919853 @default.
• W2499695817 cites W2105886206 @default.
• W2499695817 cites W2125027592 @default.
• W2499695817 cites W2133528707 @default.
• W2499695817 cites W2140279988 @default.
• W2499695817 cites W2141471714 @default.
• W2499695817 cites W2148476081 @default.
• W2499695817 cites W2161352016 @default.
• W2499695817 cites W2162689981 @default.
• W2499695817 cites W2337000942 @default.
• W2499695817 cites W2466883507 @default.
• W2499695817 cites W4247913633 @default.
• W2499695817 cites W4252708278 @default.
• W2499695817 doi "https://doi.org/10.1016/j.yrtph.2016.08.002" @default.
• W2499695817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27494949" @default.
• W2499695817 hasPublicationYear "2016" @default.
• W2499695817 type Work @default.
• W2499695817 sameAs 2499695817 @default.
• W2499695817 citedByCount "17" @default.
• W2499695817 countsByYear W24996958172016 @default.
• W2499695817 countsByYear W24996958172017 @default.
• W2499695817 countsByYear W24996958172018 @default.
• W2499695817 countsByYear W24996958172019 @default.
• W2499695817 countsByYear W24996958172020 @default.
• W2499695817 countsByYear W24996958172021 @default.
• W2499695817 countsByYear W24996958172023 @default.
• W2499695817 crossrefType "journal-article" @default.
• W2499695817 hasAuthorship W2499695817A5021828244 @default.
• W2499695817 hasAuthorship W2499695817A5033984384 @default.
• W2499695817 hasAuthorship W2499695817A5038957478 @default.
• W2499695817 hasAuthorship W2499695817A5067684050 @default.
• W2499695817 hasAuthorship W2499695817A5071850550 @default.
• W2499695817 hasConcept C126322002 @default.
• W2499695817 hasConcept C160160445 @default.
• W2499695817 hasConcept C181199279 @default.
• W2499695817 hasConcept C185592680 @default.
• W2499695817 hasConcept C2776694085 @default.
• W2499695817 hasConcept C2776877979 @default.
• W2499695817 hasConcept C2777318727 @default.
• W2499695817 hasConcept C2778176769 @default.
• W2499695817 hasConcept C2779679107 @default.
• W2499695817 hasConcept C2779896295 @default.
• W2499695817 hasConcept C2780091579 @default.
• W2499695817 hasConcept C2780306776 @default.
• W2499695817 hasConcept C2781303535 @default.
• W2499695817 hasConcept C29730261 @default.
• W2499695817 hasConcept C36880943 @default.
• W2499695817 hasConcept C503630168 @default.
• W2499695817 hasConcept C55493867 @default.
• W2499695817 hasConcept C71924100 @default.
• W2499695817 hasConcept C98274493 @default.
• W2499695817 hasConceptScore W2499695817C126322002 @default.
• W2499695817 hasConceptScore W2499695817C160160445 @default.
• W2499695817 hasConceptScore W2499695817C181199279 @default.
• W2499695817 hasConceptScore W2499695817C185592680 @default.
• W2499695817 hasConceptScore W2499695817C2776694085 @default.
• W2499695817 hasConceptScore W2499695817C2776877979 @default.
• W2499695817 hasConceptScore W2499695817C2777318727 @default.
• W2499695817 hasConceptScore W2499695817C2778176769 @default.
• W2499695817 hasConceptScore W2499695817C2779679107 @default.
• W2499695817 hasConceptScore W2499695817C2779896295 @default.
• W2499695817 hasConceptScore W2499695817C2780091579 @default.
• W2499695817 hasConceptScore W2499695817C2780306776 @default.
• W2499695817 hasConceptScore W2499695817C2781303535 @default.
• W2499695817 hasConceptScore W2499695817C29730261 @default.
• W2499695817 hasConceptScore W2499695817C36880943 @default.
• W2499695817 hasConceptScore W2499695817C503630168 @default.
• W2499695817 hasConceptScore W2499695817C55493867 @default.
• W2499695817 hasConceptScore W2499695817C71924100 @default.

• next