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• W2499966807 abstract "Assessment of the risk for osteoporotic fractures is a complex issue. The prevention of fractures through selective application of therapeutic interventions aimed at preserving bone mass is intuitively appealing, but difficult to apply. However, several issues are clear. First, if therapy to prevent bone loss is being considered, then bone mass measurements are probably necessary for several reasons: it is inappropriate to treat someone for low bone mass if bone mass is high; it is impossible to monitor the effectiveness of therapy without a baseline bone mass measurement; and there is currently no method of identifying those at either high or low risk of suffering fractures due to osteopenia without direct measurement of bone mass. Second, numerous factors appear to predict fracture risk independently of bone mass. Most of these factors have been studied in relation to hip fractures, but several seem to be associated with fractures at multiple sites. For example, a fracture after age 40 (or 50) is associated with a higher risk of other fractures later in life. In the absence of bone mass measurements, these additional risk factors could provide some basis for risk assessment, but their ideal use is in the context of a complete clinical assessment with bone mass measurements as a cornerstone. In this same vein, some women will have bone mass that is so low that interventions aimed at the preservation of bone mass may be of little value without additional protection (for example, pads for the hips), and bone mass measurements are the only way of identifying such women. There is a general agreement that fracture risk can be altered substantially with pharmacological intervention, especially with the newest generation of drugs coming onto the market." @default.
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• W2499966807 date "2001-01-01" @default.
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• W2499966807 title "Assessing Fracture Risk" @default.
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• W2499966807 doi "https://doi.org/10.1016/b978-012470862-4/50034-9" @default.
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