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• W2500060603 abstract "<b><i>Objective:</i></b> To investigate whether metabolic syndrome (MetS) may be associated with the clinical progression of benign prostatic hyperplasia (BPH). <b><i>Methods:</i></b> A total of 525 community-dwelling men (aged 45-78) with lower urinary tract symptoms (LUTS) who had complete data at 3-year follow-up were included in this prospective study. International Prostate Symptom Score (IPSS) questionnaire, prostate ultrasonography for prostate volume (PV), maximum urine flow rate (Q_max) and biological parameters were recorded. Participants were divided into a BPH with the MetS group and a BPH without the MetS group, and all received a 3-year follow-up to monitor possible correlations between LUTS/BPH clinical progression and MetS. <b><i>Results:</i></b> The results showed that MetS was associated with IPSS, Q_max and PV (p < 0.05) after 3-year follow-up. The mean change of IPSS, PV and Q_max were positively and negatively correlated with time in the BPH with MetS group during the 3-year follow-up. In addition, the BPH clinical progression rate was significantly higher in the BPH with MetS group, compared with the BPH without MetS group (p < 0.05). Diabetes mellitus (DM) and hypertension were related to increased risk of BPH clinical progression. <b><i>Conclusions:</i></b> The present results suggest that MetS, in particular, DM and hypertension, may accelerate the clinical progression of BPH in community-dwelling middle-aged and older men." @default.
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• W2500060603 date "2016-01-01" @default.
• W2500060603 modified "2023-10-15" @default.
• W2500060603 title "The Relationship between the Clinical Progression of Benign Prostatic Hyperplasia and Metabolic Syndrome: A Prospective Study" @default.
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• W2500060603 doi "https://doi.org/10.1159/000448484" @default.
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