Matches in SemOpenAlex for { <https://semopenalex.org/work/W2500498640> ?p ?o ?g. }
- W2500498640 abstract "The NMDA receptor (R) participates in many important physiological and pathological processes. For example, its activation is required for both long-term potentiation (LTP) and long-term depression (LTD) of synaptic transmission, cellular models of learning and memory. Furthermore, it may play a role in the actions of amyloid-beta on synapses as well as in the signaling leading to cell death following stroke. Until recently, these processes were thought to be mediated by ion-flux through the receptor. Using a combination of imaging and electrophysiological approaches, ion-flux independent functions of the NMDAR were recently examined. In this review, we will discuss the role of metabotropic NMDAR function in LTD and synaptic dysfunction." @default.
- W2500498640 created "2016-08-23" @default.
- W2500498640 creator A5014487102 @default.
- W2500498640 creator A5024576370 @default.
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- W2500498640 date "2016-07-28" @default.
- W2500498640 modified "2023-10-10" @default.
- W2500498640 title "The Emergence of NMDA Receptor Metabotropic Function: Insights from Imaging" @default.
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- W2500498640 doi "https://doi.org/10.3389/fnsyn.2016.00020" @default.
- W2500498640 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4963461" @default.
- W2500498640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27516738" @default.
- W2500498640 hasPublicationYear "2016" @default.
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