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- W2500686004 abstract "Molecular assays are by nature highly complex and usually quite sophisticated and esoteric. They more often resemble the assays performed in basic research laboratories than those that occur in routine clinical laboratories. This is not surprising when one considers that virtually all applications in molecular pathology have derived from research discoveries, many of them quite recent. Thus, there is a continual flow of test translation from the research to the clinical laboratory, which for the purposes of this book is the surgical pathology laboratory. This is an essential part of the evolution of molecular pathology and, indeed, the thing that makes it so exciting. Yet it causes problems for the practice of molecular pathology, especially in the area of quality assurance. It is a basic tenet of laboratory medicine that clinical and research activities are not to be mixed or performed concurrently on the same specimens or in the same space. This is because the needs and goals of research and clinical laboratories are vastly different. Research must be creative, flexible, ever-changing, and always open to new ideas and directions. It is performed by a diverse team of principal investigators, graduate students, postdoctoral fellows, and technicians, all of different backgrounds and levels of experience. Clinical laboratory practice, in contrast, must be consistent, unalteringly adherent to written protocols, and performed by licensed laboratorians who have completed mandatory training content and passed state and professional board examinations. The laboratories in which they work must be inspected regularly to ensure that these conditions are being met." @default.
- W2500686004 created "2016-08-23" @default.
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- W2500686004 date "2009-01-01" @default.
- W2500686004 modified "2023-09-24" @default.
- W2500686004 title "Quality Assurance of Molecular Assays" @default.
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- W2500686004 doi "https://doi.org/10.1016/b978-044306901-7.50007-9" @default.
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