Matches in SemOpenAlex for { <https://semopenalex.org/work/W2500884096> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2500884096 abstract "BACKGROUND. Irreversible electroporation (IRE) is (virtually) always called non-thermal despite many reports showing that significant Joule heating occurs. Our first aim is to validate with mathematical simulations that IRE as currently practiced has a non-negligible thermal response. Our second aim is to present a method that allows simple temperature estimation to aid IRE treatment planning. METHODS. We derived an approximate analytical solution of the bio-heat equation for multiple 2-needle IRE pulses in an electrically conducting medium, with and without a blood vessel, and incorporated published observations that an electric pulse increases the medium’s electric conductance. RESULTS. IRE simulation in prostate-resembling tissue shows thermal lesions with 67–92°C temperatures, which match the positions of the coagulative necrotic lesions seen in an experimental study. Simulation of IRE around a blood vessel when blood flow removes the heated blood between pulses confirms clinical observations that the perivascular tissue is thermally injured without affecting vascular patency. CONCLUSIONS. The demonstration that significant Joule heating surrounds current multiple-pulsed IRE practice may contribute to future in-depth discussions on this thermal issue. This is an important subject because it has long been under-exposed in literature. Its awareness pleads for preventing IRE from calling “non-thermal” in future publications, in order to provide IRE-users with the most accurate information possible. The prospect of thermal treatment planning as outlined in this paper likely aids to the important further successful dissemination of IRE in interventional medicine. Prostate 75:332–335, 2015." @default.
- W2500884096 created "2016-08-23" @default.
- W2500884096 creator A5004017655 @default.
- W2500884096 creator A5022230020 @default.
- W2500884096 creator A5043837012 @default.
- W2500884096 creator A5060053979 @default.
- W2500884096 creator A5062805202 @default.
- W2500884096 creator A5064093864 @default.
- W2500884096 creator A5065033026 @default.
- W2500884096 creator A5078824354 @default.
- W2500884096 date "2015-01-01" @default.
- W2500884096 modified "2023-09-27" @default.
- W2500884096 title "2 DepartmentofUrology,AcademicMedicalCenter,UniversityofAmsterdam,Amsterdam,TheNetherlands 3 DepartmentofPathology,AcademicMedicalCenter,UniversityofAmsterdam,Amsterdam,TheNetherlands 4 DepartmentofExperimentalSurgery,AcademicMedicalCenter,UniversityofAmsterdam,Amsterdam," @default.
- W2500884096 cites W1998962655 @default.
- W2500884096 cites W2000646988 @default.
- W2500884096 cites W2008522415 @default.
- W2500884096 cites W2016854542 @default.
- W2500884096 cites W2019410912 @default.
- W2500884096 cites W2039975310 @default.
- W2500884096 cites W2075371851 @default.
- W2500884096 cites W2085749017 @default.
- W2500884096 cites W2092447216 @default.
- W2500884096 cites W2122122695 @default.
- W2500884096 cites W2126573497 @default.
- W2500884096 cites W2129670488 @default.
- W2500884096 cites W2146135137 @default.
- W2500884096 hasPublicationYear "2015" @default.
- W2500884096 type Work @default.
- W2500884096 sameAs 2500884096 @default.
- W2500884096 citedByCount "0" @default.
- W2500884096 crossrefType "journal-article" @default.
- W2500884096 hasAuthorship W2500884096A5004017655 @default.
- W2500884096 hasAuthorship W2500884096A5022230020 @default.
- W2500884096 hasAuthorship W2500884096A5043837012 @default.
- W2500884096 hasAuthorship W2500884096A5060053979 @default.
- W2500884096 hasAuthorship W2500884096A5062805202 @default.
- W2500884096 hasAuthorship W2500884096A5064093864 @default.
- W2500884096 hasAuthorship W2500884096A5065033026 @default.
- W2500884096 hasAuthorship W2500884096A5078824354 @default.
- W2500884096 hasConcept C104317684 @default.
- W2500884096 hasConcept C117926987 @default.
- W2500884096 hasConcept C136229726 @default.
- W2500884096 hasConcept C142724271 @default.
- W2500884096 hasConcept C158846371 @default.
- W2500884096 hasConcept C159985019 @default.
- W2500884096 hasConcept C164705383 @default.
- W2500884096 hasConcept C185592680 @default.
- W2500884096 hasConcept C186852380 @default.
- W2500884096 hasConcept C192562407 @default.
- W2500884096 hasConcept C21613296 @default.
- W2500884096 hasConcept C2778716261 @default.
- W2500884096 hasConcept C2780167933 @default.
- W2500884096 hasConcept C41008148 @default.
- W2500884096 hasConcept C55493867 @default.
- W2500884096 hasConcept C71924100 @default.
- W2500884096 hasConcept C76155785 @default.
- W2500884096 hasConcept C94915269 @default.
- W2500884096 hasConceptScore W2500884096C104317684 @default.
- W2500884096 hasConceptScore W2500884096C117926987 @default.
- W2500884096 hasConceptScore W2500884096C136229726 @default.
- W2500884096 hasConceptScore W2500884096C142724271 @default.
- W2500884096 hasConceptScore W2500884096C158846371 @default.
- W2500884096 hasConceptScore W2500884096C159985019 @default.
- W2500884096 hasConceptScore W2500884096C164705383 @default.
- W2500884096 hasConceptScore W2500884096C185592680 @default.
- W2500884096 hasConceptScore W2500884096C186852380 @default.
- W2500884096 hasConceptScore W2500884096C192562407 @default.
- W2500884096 hasConceptScore W2500884096C21613296 @default.
- W2500884096 hasConceptScore W2500884096C2778716261 @default.
- W2500884096 hasConceptScore W2500884096C2780167933 @default.
- W2500884096 hasConceptScore W2500884096C41008148 @default.
- W2500884096 hasConceptScore W2500884096C55493867 @default.
- W2500884096 hasConceptScore W2500884096C71924100 @default.
- W2500884096 hasConceptScore W2500884096C76155785 @default.
- W2500884096 hasConceptScore W2500884096C94915269 @default.
- W2500884096 hasLocation W25008840961 @default.
- W2500884096 hasOpenAccess W2500884096 @default.
- W2500884096 hasPrimaryLocation W25008840961 @default.
- W2500884096 isParatext "false" @default.
- W2500884096 isRetracted "false" @default.
- W2500884096 magId "2500884096" @default.
- W2500884096 workType "article" @default.