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- W2501887844 abstract "The present study was conducted with the aim of evaluating the antiulcer activity of ocimum sanctum and to explore its mechanism of action. In this study, ocimum sanctum leaf extract was investigated for its activity against aspirin induced gastric ulcers in albino rats. The drug showed significant activity in the doses of 100 mg/kg and 200 mg/kg. To explore the mechanism, its activity was observed on oxytocin induced contractions in rat uterus. It exhibited a significant potentiation of the height of contraction induced by oxytocin. The maximum potentiation was observed in the dose of 0.5 mg/ml which may be due to enhanced synthesis of prostaglandins since they are mediators of uterine contractions. This indicates a cytoprotective mechanism for the antiulcer activity of ocimum sanctum." @default.
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- W2501887844 date "2012-01-01" @default.
- W2501887844 modified "2023-09-26" @default.
- W2501887844 title "Evaluation Of Antiulcer Activity Of Ocimum Sanctum And Its Mechanism In Animal Models" @default.
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- W2501887844 doi "https://doi.org/10.5580/2c61" @default.
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