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- W2502154141 abstract "Stimulated blood platelets secrete a high molecular weight glycoprotein, thrombospondin, located in alpha granules. Thrombospondin may play an important role in the formation of haemostatic plugs. The aim of this study was to characterize by competitive binding assays four monoclonal antibodies directed against thrombospondin. Competitive binding assays were performed using thrombospondin purified by FPLC on a Mono Q anion-exchange column. Results showed that these monoclonal antibodies were directed against two different epitopes on thrombospondin. These results were confirmed by a double antibody sandwich test. These monoclonal antibodies should offer a useful approach for the understanding of the physiological role of thrombospondin in platelets." @default.
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- W2502154141 date "1985-01-01" @default.
- W2502154141 modified "2023-09-26" @default.
- W2502154141 title "Characterization of Monoclonal Antibodies Specific for a High Molecular Weight Glycoprotein Secreted from Activated Human Blood Platelets" @default.
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- W2502154141 doi "https://doi.org/10.1016/b978-0-08-031739-7.50202-0" @default.
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