Matches in SemOpenAlex for { <https://semopenalex.org/work/W2502470180> ?p ?o ?g. }
- W2502470180 endingPage "547" @default.
- W2502470180 startingPage "535" @default.
- W2502470180 abstract "Cryptosporidium is a major cause of moderate-to-severe diarrhoea in humans worldwide, second only to rotavirus. Due to the wide host range and environmental persistence of this parasite, cryptosporidiosis can be zoonotic and associated with foodborne and waterborne outbreaks. Currently, 31 species are recognized as valid, and of these, Cryptosporidium hominis and Cryptosporidium parvum are responsible for the majority of infections in humans. The immune status of the host, both innate and adaptive immunity, has a major impact on the severity of the disease and its prognosis. Immunocompetent individuals typically experience self-limiting diarrhoea and transient gastroenteritis lasting up to 2 weeks and recover without treatment, suggesting an efficient host antiparasite immune response. Immunocompromised individuals can suffer from intractable diarrhoea, which can be fatal. Effective drug treatments and vaccines are not yet available. As a result of this, the close cooperation and interaction between veterinarians, health physicians, environmental managers and public health operators is essential to properly control this disease. This review focuses on a One Health approach to prophylaxis, including the importance of understanding transmission routes for zoonotic Cryptosporidium species, improved sanitation and better risk management, improved detection, diagnosis and treatment and the prospect of an effective anticryptosporidial vaccine." @default.
- W2502470180 created "2016-08-23" @default.
- W2502470180 creator A5033295595 @default.
- W2502470180 creator A5042914056 @default.
- W2502470180 creator A5044401889 @default.
- W2502470180 date "2016-09-01" @default.
- W2502470180 modified "2023-10-16" @default.
- W2502470180 title "<i>Cryptosporidium</i> in humans and animals—a one health approach to prophylaxis" @default.
- W2502470180 cites W1169533616 @default.
- W2502470180 cites W1177745140 @default.
- W2502470180 cites W1498130665 @default.
- W2502470180 cites W1543070703 @default.
- W2502470180 cites W1544865769 @default.
- W2502470180 cites W1577149967 @default.
- W2502470180 cites W1649546725 @default.
- W2502470180 cites W165449188 @default.
- W2502470180 cites W1668595180 @default.
- W2502470180 cites W1692465622 @default.
- W2502470180 cites W1794491409 @default.
- W2502470180 cites W1816233761 @default.
- W2502470180 cites W1821981622 @default.
- W2502470180 cites W1837973421 @default.
- W2502470180 cites W1917485115 @default.
- W2502470180 cites W1928122503 @default.
- W2502470180 cites W1937283342 @default.
- W2502470180 cites W1963777427 @default.
- W2502470180 cites W1967382132 @default.
- W2502470180 cites W1969182385 @default.
- W2502470180 cites W1970179234 @default.
- W2502470180 cites W1970428667 @default.
- W2502470180 cites W1972252126 @default.
- W2502470180 cites W1972322341 @default.
- W2502470180 cites W1972816772 @default.
- W2502470180 cites W1973449369 @default.
- W2502470180 cites W1975470757 @default.
- W2502470180 cites W1976335281 @default.
- W2502470180 cites W1979682945 @default.
- W2502470180 cites W1979900779 @default.
- W2502470180 cites W1987433193 @default.
- W2502470180 cites W1987832932 @default.
- W2502470180 cites W1993092899 @default.
- W2502470180 cites W1993192822 @default.
- W2502470180 cites W1994445791 @default.
- W2502470180 cites W1996959137 @default.
- W2502470180 cites W1997032362 @default.
- W2502470180 cites W1997464175 @default.
- W2502470180 cites W1998328552 @default.
- W2502470180 cites W1999764400 @default.
- W2502470180 cites W2000935555 @default.
- W2502470180 cites W2001828173 @default.
- W2502470180 cites W2004799574 @default.
- W2502470180 cites W2005516777 @default.
- W2502470180 cites W2010146173 @default.
- W2502470180 cites W2010944514 @default.
- W2502470180 cites W2012910114 @default.
- W2502470180 cites W2014638802 @default.
- W2502470180 cites W2015810688 @default.
- W2502470180 cites W2015912955 @default.
- W2502470180 cites W2017667735 @default.
- W2502470180 cites W2018922271 @default.
- W2502470180 cites W2020932654 @default.
- W2502470180 cites W2021821299 @default.
- W2502470180 cites W2022848949 @default.
- W2502470180 cites W2024332150 @default.
- W2502470180 cites W2024569160 @default.
- W2502470180 cites W2026429184 @default.
- W2502470180 cites W2027384954 @default.
- W2502470180 cites W2027598370 @default.
- W2502470180 cites W2031374169 @default.
- W2502470180 cites W2031992346 @default.
- W2502470180 cites W2032298947 @default.
- W2502470180 cites W2032825725 @default.
- W2502470180 cites W2032854797 @default.
- W2502470180 cites W2033009980 @default.
- W2502470180 cites W2036244972 @default.
- W2502470180 cites W2037566397 @default.
- W2502470180 cites W2038120139 @default.
- W2502470180 cites W2039710005 @default.
- W2502470180 cites W2039864475 @default.
- W2502470180 cites W2044109669 @default.
- W2502470180 cites W2044430836 @default.
- W2502470180 cites W2045601768 @default.
- W2502470180 cites W2046269838 @default.
- W2502470180 cites W2048104310 @default.
- W2502470180 cites W2050894016 @default.
- W2502470180 cites W2052470422 @default.
- W2502470180 cites W2052829066 @default.
- W2502470180 cites W2053870588 @default.
- W2502470180 cites W2054358003 @default.
- W2502470180 cites W2058977096 @default.
- W2502470180 cites W2060093931 @default.
- W2502470180 cites W2061669522 @default.
- W2502470180 cites W2065448524 @default.
- W2502470180 cites W2068093732 @default.
- W2502470180 cites W2069321927 @default.
- W2502470180 cites W2069493081 @default.
- W2502470180 cites W2071148685 @default.
- W2502470180 cites W2073229622 @default.