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- W2502476800 abstract "Abstract Polyphenols play a significant role in vision physiology and antioxidant protection of the eye, as suggested by in vitro studies. Flavonoids act on various etiologic factors responsible for the development of ocular diseases. In vitro studies demonstrate that flavonoids interact directly with rhodopsin and modulate visual pigment function and that flavonoids protect retinal cells from oxidative stress-induced cell death, a neuroprotective property of significance. Possible mitigation of age-related vision pathologies related to oxidative damage by flavonoids is supported by in vitro studies. There is a need to explore the potential for improved vision health through dietary intake of polyphenols. Based on animal studies, dietary curcumin may have potential benefits in the prevention of retinopathy in diabetes. The mechanism of beneficial effects of polyphenols involves scavenging the free radicals, reducing advanced glycation end-product formation, aldose reductase inhibition, anti-inflammatory activity, effect on ocular blood flow, and direct effect on signal transduction." @default.
- W2502476800 created "2016-08-23" @default.
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- W2502476800 date "2014-01-01" @default.
- W2502476800 modified "2023-10-10" @default.
- W2502476800 title "Polyphenols in Vision and Eye Health" @default.
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- W2502476800 doi "https://doi.org/10.1016/b978-0-12-401717-7.00042-3" @default.
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