Matches in SemOpenAlex for { <https://semopenalex.org/work/W250264098> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W250264098 endingPage "3" @default.
- W250264098 startingPage "421" @default.
- W250264098 abstract "To evaluate the efficacy,clinical benefits and toxicities of gemcitabine combined with erlotinib for advanced pancreatic cancer.Clinical data of 20 patients with advanced pancreatic cancer treated with gemcitabine 1000 mg/m2 on day 1 and day 8 (repeated every 21 days) plus erlotinib 100-150 mg/d at Peking Union Medical College Hospital was reviewed retrospectively.No patient achieved complete remission or partial remission, 11 patients (55%) had stable disease, and 9 patients (45%) experienced disease progression. The disease control rate was 55%, and clinical benefit rate was 30%. The median progression free survival was 4.0 months, and the median overall survival was 8 months. The total incidence of hematologic toxicity was 70%, including 15% of grade 3-4 leucopenia and 5% of grade 3-4 thrombocytopenia. Eleven patients (55%) had rash, which were all grade 1-2. One patient had grade 2 diarrhea and five had grade 1 transaminase elevation. No chemotherapy-related death occurred.Gemcitabine combined with erlotinib is an effective regimen for pancreatic cancer with good clinical tolerance. The most common adverse events are hematologic toxicities and rash." @default.
- W250264098 created "2016-06-24" @default.
- W250264098 creator A5028640794 @default.
- W250264098 creator A5029385936 @default.
- W250264098 creator A5060070844 @default.
- W250264098 date "2010-08-01" @default.
- W250264098 modified "2023-09-26" @default.
- W250264098 title "[Efficacy of gemcitabine combined with erlotinib in patients with advanced pancreatic cancer]." @default.
- W250264098 doi "https://doi.org/10.3881/j.issn.1000-503x.2010.04.013" @default.
- W250264098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20868602" @default.
- W250264098 hasPublicationYear "2010" @default.
- W250264098 type Work @default.
- W250264098 sameAs 250264098 @default.
- W250264098 citedByCount "3" @default.
- W250264098 countsByYear W2502640982016 @default.
- W250264098 countsByYear W2502640982018 @default.
- W250264098 crossrefType "journal-article" @default.
- W250264098 hasAuthorship W250264098A5028640794 @default.
- W250264098 hasAuthorship W250264098A5029385936 @default.
- W250264098 hasAuthorship W250264098A5060070844 @default.
- W250264098 hasConcept C121608353 @default.
- W250264098 hasConcept C126322002 @default.
- W250264098 hasConcept C141071460 @default.
- W250264098 hasConcept C143998085 @default.
- W250264098 hasConcept C197934379 @default.
- W250264098 hasConcept C2776694085 @default.
- W250264098 hasConcept C2778087573 @default.
- W250264098 hasConcept C2778570526 @default.
- W250264098 hasConcept C2779438470 @default.
- W250264098 hasConcept C2780210213 @default.
- W250264098 hasConcept C2780258809 @default.
- W250264098 hasConcept C2781413609 @default.
- W250264098 hasConcept C71924100 @default.
- W250264098 hasConcept C90924648 @default.
- W250264098 hasConceptScore W250264098C121608353 @default.
- W250264098 hasConceptScore W250264098C126322002 @default.
- W250264098 hasConceptScore W250264098C141071460 @default.
- W250264098 hasConceptScore W250264098C143998085 @default.
- W250264098 hasConceptScore W250264098C197934379 @default.
- W250264098 hasConceptScore W250264098C2776694085 @default.
- W250264098 hasConceptScore W250264098C2778087573 @default.
- W250264098 hasConceptScore W250264098C2778570526 @default.
- W250264098 hasConceptScore W250264098C2779438470 @default.
- W250264098 hasConceptScore W250264098C2780210213 @default.
- W250264098 hasConceptScore W250264098C2780258809 @default.
- W250264098 hasConceptScore W250264098C2781413609 @default.
- W250264098 hasConceptScore W250264098C71924100 @default.
- W250264098 hasConceptScore W250264098C90924648 @default.
- W250264098 hasIssue "4" @default.
- W250264098 hasLocation W2502640981 @default.
- W250264098 hasOpenAccess W250264098 @default.
- W250264098 hasPrimaryLocation W2502640981 @default.
- W250264098 hasRelatedWork W1931508686 @default.
- W250264098 hasRelatedWork W1966165324 @default.
- W250264098 hasRelatedWork W1976626931 @default.
- W250264098 hasRelatedWork W1986253711 @default.
- W250264098 hasRelatedWork W2001996041 @default.
- W250264098 hasRelatedWork W2020242834 @default.
- W250264098 hasRelatedWork W2022501291 @default.
- W250264098 hasRelatedWork W2030855325 @default.
- W250264098 hasRelatedWork W2036281035 @default.
- W250264098 hasRelatedWork W2071125719 @default.
- W250264098 hasRelatedWork W2073311244 @default.
- W250264098 hasRelatedWork W2156057121 @default.
- W250264098 hasRelatedWork W2158134441 @default.
- W250264098 hasRelatedWork W2413203029 @default.
- W250264098 hasRelatedWork W2610388626 @default.
- W250264098 hasRelatedWork W2622744225 @default.
- W250264098 hasRelatedWork W2777682849 @default.
- W250264098 hasRelatedWork W2903623792 @default.
- W250264098 hasRelatedWork W2993398695 @default.
- W250264098 hasRelatedWork W2591240441 @default.
- W250264098 hasVolume "32" @default.
- W250264098 isParatext "false" @default.
- W250264098 isRetracted "false" @default.
- W250264098 magId "250264098" @default.
- W250264098 workType "article" @default.