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- W2502850046 abstract "The concept of the fetus and placenta functioning as a combined endocrine system (the fetoplacental unit) was first elaborated by Diczfalusy, based on the recognition that, although the fetus and placenta each lack certain key enzymes involved in steroidogenesis, their complementary function as a single endocrine unit allows synthesis of a wide range of steroids. For example, the fetus contains all the enzymes required for cholesterol synthesis, as well as many enzymes involved in sulfurylation and hydroxylation of steroids. These fetal enzymes are not found in the placenta, however, which possesses sulfatases and characteristic dehydrogenases not found in the fetus. The interaction of fetal, placental, and maternal biosynthetic functions is best illustrated by the formation of estriol (Fig 1)." @default.
- W2502850046 created "2016-08-23" @default.
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- W2502850046 date "1984-02-01" @default.
- W2502850046 modified "2023-09-23" @default.
- W2502850046 title "Endocrinology of the Fetoplacental Unit: Role of Estrogen Assays" @default.
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- W2502850046 doi "https://doi.org/10.1093/labmed/15.2.95" @default.
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