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- W2503780426 abstract "The application of epigenomic techniques to classical twin studies has elucidated the metastable nature of epigenetic signals throughout the course of development, a process that appears to be strongly influenced by the intrauterine environment and the chorionicity of the twins investigated. Comparisons of monozygotic to dizygotic twin epigenome profiles is providing evidence for a heritable influence on epigenetic factors, mediated by genetic and possibly nongenetic mechanisms. Our growing understanding of the molecular epigenetic differences between genetically identical individuals may help to address the yet unsolved issues in complex non-Mendelian disease, including monozygotic twin discordance and the missing heritability." @default.
- W2503780426 created "2016-08-23" @default.
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- W2503780426 date "2013-12-01" @default.
- W2503780426 modified "2023-09-25" @default.
- W2503780426 title "The Role of Epigenomics in Genetically Identical Individuals" @default.
- W2503780426 doi "https://doi.org/10.1093/med/9780199855452.003.0003" @default.
- W2503780426 hasPublicationYear "2013" @default.
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