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- W2504205423 endingPage "1244" @default.
- W2504205423 startingPage "1232" @default.
- W2504205423 abstract "Traumatic brain injury is a problem that affects millions of Americans yearly and for which there is no definitive treatment that improves outcome. Continuous brain tissue oxygen (P<sub>btO<sub>2</sub></sub>) monitoring is a complement to traditional brain monitoring techniques, such as intracranial pressure and cerebral perfusion pressure. P<sub>btO<sub>2</sub></sub> monitoring has not yet become a clinical standard of care, due to several unresolved questions. In this review, we discuss the rationale and technology of P<sub>btO<sub>2</sub></sub> monitoring. We review the literature, both historic and current, and show that continuous P<sub>btO<sub>2</sub></sub> monitoring is feasible and useful in patient management. P<sub>btO<sub>2</sub></sub> numbers reflect cerebral blood flow and oxygen diffusion. Thus, continuous monitoring of P<sub>btO<sub>2</sub></sub> yields important information about both the brain and the lung. The preclinical and clinical studies demonstrating these findings are discussed. In this review, we demonstrate that patient management in a P<sub>btO<sub>2</sub></sub>-directed fashion is not the sole answer to the problem of treating traumatic brain injury but is an important adjunct to the armamentarium of multimodal neuromonitoring." @default.
- W2504205423 created "2016-08-23" @default.
- W2504205423 creator A5014092617 @default.
- W2504205423 creator A5044793226 @default.
- W2504205423 creator A5076261073 @default.
- W2504205423 date "2016-07-19" @default.
- W2504205423 modified "2023-10-18" @default.
- W2504205423 title "Brain Tissue Oxygen Monitoring and the Intersection of Brain and Lung: A Comprehensive Review" @default.
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