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- W2504209652 abstract "Asthma is a complex disease, which is influenced by the interaction among the genetic background, environmental exposures and life-style factors. The association between genetic factors and health outcomes is usually evaluated by using classic statistical methods that test the effect of a single genetic variant at a time, by controlling for the multiple hypotheses testing. For almost all complex traits, this strategy is suboptimal because the identified genetic effects could only account for a minor portion of the estimated trait heritability. Moreover, continuous outcomes should be used to catch the heterogeneity of asthma phenotypes that may result from different risk factors." @default.
- W2504209652 created "2016-08-23" @default.
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- W2504209652 date "2016-05-26" @default.
- W2504209652 modified "2023-09-23" @default.
- W2504209652 title "Statistical approaches for the evaluation of genetic associations in complex diseases: the heterogeneity of asthma phenotypes" @default.
- W2504209652 hasPublicationYear "2016" @default.
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