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- W2504785265 abstract "A simple competitive screening method has been developed for the characterization of monoclonal antibodies to human chorionic somatomammotropin produced in our laboratory. The method using labeled antigen is easily adaptable to monoclonal antibodies against other soluble antigens. Our proposed method allows the evaluation of the degree of binding of the antibody to the antigen, and of cross-reaction with related molecules (human growth hormone and ovine prolactin). In order to determine the affinity constants of the antibodies, the positive clones have been further characterized by solid-phase radioimmunoassay, and the affinity constants, ranging from 10 to 109 M-1, were determined by non linear regression analysis." @default.
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- W2504785265 date "1985-01-01" @default.
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- W2504785265 title "Competitive Screening and Determination of the Affinity Constants for the Characterization of Monoclonal Antibodies Against Human Chorionic Somatomammotropin" @default.
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- W2504785265 doi "https://doi.org/10.1016/b978-0-08-031739-7.50229-9" @default.
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