Matches in SemOpenAlex for { <https://semopenalex.org/work/W2504865277> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2504865277 abstract "Some fatty acids, such as CLA (conjugated linoleic acid) and n-3 fatty acids modulate immune and inflammatory response in ruminants and monogastrics; their supplementation alters fatty acids profile of meat and milk, enhancing their nutritional quality. However, it is still unclear if their addition causes oxidative damage to animals. Nuclear factor E2-related factor 2 (Nrf2) plays an important role in cellular defenses against oxidative stress, indeed it produces a rapid induction of its target genes involved in antioxidant response. The aim of the project is to investigate the activation of Nrf2 in luciferase reporter mice fed different amount of n-3 PUFA in the diet (7,5% lard, 7,5% tuna oil, 20 % lard and 20%tuna oil). Forty-eight reporter mice are divided into three groups: male, intact female and ovariectomized female. Each group is split in four subgroups fed different diets. Oxidative status will be studied monitoring Nrf2’s activation with in vivo bioluminescent imaging. The inflammatory and immune response will be assessed using calprotectin and lactoferrin levels in faecal samples that are non-invasive techniques. The trial is still in progress: on the 62nd day, animals will be sacrificed after a challenge in order to measure the different effects of diets and +/- oestrogen on stress response. Finally, the post mortem analysis will be carried on extract organs. Data obtained will be analysed using statistical procedures and results will improve the knowledge about interaction between omega-3 fatty acids and animals’ oxidative status." @default.
- W2504865277 created "2016-08-23" @default.
- W2504865277 creator A5055666393 @default.
- W2504865277 creator A5060234266 @default.
- W2504865277 creator A5077375359 @default.
- W2504865277 creator A5084329510 @default.
- W2504865277 creator A5085795821 @default.
- W2504865277 date "2016-06-06" @default.
- W2504865277 modified "2023-09-23" @default.
- W2504865277 title "Nuclear factor E2-related factor 2’s activation in transgenic mice fed with high dosage of fish oil." @default.
- W2504865277 cites W1983405965 @default.
- W2504865277 cites W2015392958 @default.
- W2504865277 cites W2117551116 @default.
- W2504865277 cites W2121044256 @default.
- W2504865277 cites W2536780999 @default.
- W2504865277 doi "https://doi.org/10.13130/2283-3927/7090" @default.
- W2504865277 hasPublicationYear "2016" @default.
- W2504865277 type Work @default.
- W2504865277 sameAs 2504865277 @default.
- W2504865277 citedByCount "0" @default.
- W2504865277 crossrefType "journal-article" @default.
- W2504865277 hasAuthorship W2504865277A5055666393 @default.
- W2504865277 hasAuthorship W2504865277A5060234266 @default.
- W2504865277 hasAuthorship W2504865277A5077375359 @default.
- W2504865277 hasAuthorship W2504865277A5084329510 @default.
- W2504865277 hasAuthorship W2504865277A5085795821 @default.
- W2504865277 hasConcept C126322002 @default.
- W2504865277 hasConcept C150903083 @default.
- W2504865277 hasConcept C185592680 @default.
- W2504865277 hasConcept C19038510 @default.
- W2504865277 hasConcept C203014093 @default.
- W2504865277 hasConcept C207001950 @default.
- W2504865277 hasConcept C2776151105 @default.
- W2504865277 hasConcept C2778004101 @default.
- W2504865277 hasConcept C2779170986 @default.
- W2504865277 hasConcept C2779780233 @default.
- W2504865277 hasConcept C2779946292 @default.
- W2504865277 hasConcept C2780532849 @default.
- W2504865277 hasConcept C2780809830 @default.
- W2504865277 hasConcept C2909208804 @default.
- W2504865277 hasConcept C31903555 @default.
- W2504865277 hasConcept C505870484 @default.
- W2504865277 hasConcept C543025807 @default.
- W2504865277 hasConcept C55493867 @default.
- W2504865277 hasConcept C71924100 @default.
- W2504865277 hasConcept C86803240 @default.
- W2504865277 hasConcept C8891405 @default.
- W2504865277 hasConceptScore W2504865277C126322002 @default.
- W2504865277 hasConceptScore W2504865277C150903083 @default.
- W2504865277 hasConceptScore W2504865277C185592680 @default.
- W2504865277 hasConceptScore W2504865277C19038510 @default.
- W2504865277 hasConceptScore W2504865277C203014093 @default.
- W2504865277 hasConceptScore W2504865277C207001950 @default.
- W2504865277 hasConceptScore W2504865277C2776151105 @default.
- W2504865277 hasConceptScore W2504865277C2778004101 @default.
- W2504865277 hasConceptScore W2504865277C2779170986 @default.
- W2504865277 hasConceptScore W2504865277C2779780233 @default.
- W2504865277 hasConceptScore W2504865277C2779946292 @default.
- W2504865277 hasConceptScore W2504865277C2780532849 @default.
- W2504865277 hasConceptScore W2504865277C2780809830 @default.
- W2504865277 hasConceptScore W2504865277C2909208804 @default.
- W2504865277 hasConceptScore W2504865277C31903555 @default.
- W2504865277 hasConceptScore W2504865277C505870484 @default.
- W2504865277 hasConceptScore W2504865277C543025807 @default.
- W2504865277 hasConceptScore W2504865277C55493867 @default.
- W2504865277 hasConceptScore W2504865277C71924100 @default.
- W2504865277 hasConceptScore W2504865277C86803240 @default.
- W2504865277 hasConceptScore W2504865277C8891405 @default.
- W2504865277 hasLocation W25048652771 @default.
- W2504865277 hasOpenAccess W2504865277 @default.
- W2504865277 hasPrimaryLocation W25048652771 @default.
- W2504865277 hasRelatedWork W1549312137 @default.
- W2504865277 hasRelatedWork W1954317073 @default.
- W2504865277 hasRelatedWork W1998329763 @default.
- W2504865277 hasRelatedWork W2026266815 @default.
- W2504865277 hasRelatedWork W2034526286 @default.
- W2504865277 hasRelatedWork W2053334642 @default.
- W2504865277 hasRelatedWork W2081227792 @default.
- W2504865277 hasRelatedWork W2101714792 @default.
- W2504865277 hasRelatedWork W2121175612 @default.
- W2504865277 hasRelatedWork W2158121949 @default.
- W2504865277 hasRelatedWork W2270077085 @default.
- W2504865277 hasRelatedWork W2591296604 @default.
- W2504865277 hasRelatedWork W2735714472 @default.
- W2504865277 hasRelatedWork W2768665544 @default.
- W2504865277 hasRelatedWork W2941970111 @default.
- W2504865277 hasRelatedWork W2946931237 @default.
- W2504865277 hasRelatedWork W2986153397 @default.
- W2504865277 hasRelatedWork W3036892737 @default.
- W2504865277 hasRelatedWork W3047144339 @default.
- W2504865277 hasRelatedWork W3195164907 @default.
- W2504865277 hasVolume "3" @default.
- W2504865277 isParatext "false" @default.
- W2504865277 isRetracted "false" @default.
- W2504865277 magId "2504865277" @default.
- W2504865277 workType "article" @default.