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- W2505371474 abstract "Abstract The term synapse was coined by Sherrington to describe the points of contact between the terminals of a neuron and another cell or neuron. Synaptic transmission represents the process by which communication between neurons occurs, i.e., when an action potential is propagated along the axon of one neuron and produces a postsynaptic response in the target cell or neuron. This process is a specialized form of intercellular communication and exhibits many unique features. In particular, it depends on the existence of a relatively large number of chemical messengers, or neurotransmitters together with their specific receptors and associated signal transduction systems. Synaptic transmission spans several time domains ranging from a few milliseconds to hours or days. Synaptic integration refers to the dynamics of synaptic transmission because the efficacy of transmission is dependent on the frequency of the signals in the presynaptic elements, as well as the past history of activity. These characteristics of frequency-dependency and activity-dependency form the basis for the adaptive properties of synaptic transmission, and are responsible for the critical role of synapses in information processing and storage, memory." @default.
- W2505371474 created "2016-08-23" @default.
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- W2505371474 date "2017-01-01" @default.
- W2505371474 modified "2023-09-25" @default.
- W2505371474 title "Synapses and Synaptic Transmission and Integration ☆" @default.
- W2505371474 doi "https://doi.org/10.1016/b978-0-12-809324-5.03180-1" @default.
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