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- W2505769066 abstract "OBJECTIVE: To determine correlation of cardiac troponin T elevation in acute ischemic stroke with clinical outcome and potential cardiac sources of embolism. BACKGROUND: Elevated of plasma cardiac troponin T, biomarker of myocardial necrosis, is often seen in acute ischemic stroke patients. Although previous studies aimed to reveal the mechanism of elevated cardiac troponin T in ischemic stroke, the mechanism is not clearly defined. DESIGN/METHODS: We retrospectively reviewed 196 patients with acute ischemic stroke who admitted between October 2013 and September 2014, The Cardiac troponin T level, initial National Institutes of Health Stroke Scale and modified Rankin Scale at discharge were analyzed. Normal troponin T range of our lab is below 14ng/l. RESULTS: The mean age was 64.8 (±14.821) and 118 (60.2[percnt]) patients were male. Forty-eight (24.4[percnt]) out of 196 patients showed elevated cardiac troponin T level at admission. Patients with elevated cardiac troponin T level was older than patients with normal cardiac troponin T level. (73.4 vs. 62.0; p=0.000). Patients with elevated cardiac troponin T had higher initial National Institutes of Health Stroke Scale (6.31 vs. 3.85; p=0.02), and more poor outcome (modified Rankin Scale at discharge, 2.81 vs. 1.91; p=0.001). The cardiac troponin T levels of all patients who had known potential cardiac sources of embolism were higher than no risk group (0.024 vs. 0.11; p=0.025), but specific sources like atrial fibrillation (0.032 vs. 0.012; p=0.057) and hypokinesia/akinesia of LV (0.037 vs 0.013; p=0.195) was not shown significant correlation. CONCLUSIONS: Elevated cardiac troponin T level after acute ischemic stroke is frequently seen and suggests likely to present of potential cardiac sources of embolism. However, there is no correlation with specific sources. Study Supported by: Disclosure: Dr. Kim has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Lee has nothing to disclose." @default.
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- W2505769066 date "2015-04-06" @default.
- W2505769066 modified "2023-09-24" @default.
- W2505769066 title "Elevated Cardiac Troponin-T in acute ischemic stroke (P4.286)" @default.
- W2505769066 hasPublicationYear "2015" @default.
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