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- W2506327586 abstract "Summary Introduction In this study, we aimed to evaluate Red blood cell distribution width (RDW) in patients with acute rheumatic carditis during the acute phase and after anti‐inflammatory therapy. Methods Pediatric patients diagnosed with acute rheumatic carditis ( ARC ) between 2006 and 2014 and age‐ and sex‐matched controls were retrospectively analyzed. At the time of diagnosis and after 2 months of medical therapy, we reviewed the obtained demographic features; echocardiographic data; complete blood count reports, including RDW; acute phase reactants, including C‐reactive protein; and erythrocyte sedimentation rate values. Results The number of the cases with ARC and age‐ and sex‐matched controls were 100 and 110, respectively. The mean age of patients was 11.6 ± 2.5 years. WBC and platelet counts, RDW were found to be significantly higher in patient group compared with controls at the time of diagnosis, prior to the onset of treatment. RDW , platelet count, CRP , and ESR levels significantly decreased after an 8 weeks of medical treatment. RDW values after the medical treatment were still significantly higher compared with controls. RDW values were significantly higher in patients with multiple valvular involvement both prior to and after the treatment. Moreover, we found a significant and positive correlation between the RDW and the severity of mitral regurgitation in our patients ( r : 0.46, P < 0.001). Conclusions High levels of RDW after initial medical treatment may indicate an ongoing subtle inflammatory process that leads to future stenotic valvular lesions. However, long‐term follow‐up studies are needed involving adulthood period to support this hypothesis." @default.
- W2506327586 created "2016-08-23" @default.
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- W2506327586 date "2016-07-20" @default.
- W2506327586 modified "2023-09-30" @default.
- W2506327586 title "Red blood cell distribution width: can it be a predictive marker for long-term valvular involvement in children with acute rheumatic carditis?" @default.
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- W2506327586 doi "https://doi.org/10.1111/ijlh.12544" @default.
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