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- W2506460219 abstract "Since the initial efforts began to perform medical research using human specimens, value has been placed on the ability to have access to specimens to better understand the nature of disease. Over time, research protocols have been devised to increase consistency in how specimens are handled in order to improve the quality of the results obtained. It has only been in recent years that scientists have begun to appreciate how the condition of the patient at the time the biological specimen is obtained and even subtle differences in how a specimen is handled may significantly impact the molecular profile of that specimen, and consequently the outcomes from assays in which the specimen, or extracts from the specimen are used. The purpose of this chapter is to review critical considerations that should be made when performing research using patient samples, to provide guidance on how those samples most effectively can be collected and processed, and finally, how processing procedures can be documented effectively and reported to allow for scientific review of findings and support the reproducibility of the research outcomes in subsequent studies." @default.
- W2506460219 created "2016-08-23" @default.
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- W2506460219 date "2012-01-01" @default.
- W2506460219 modified "2023-09-27" @default.
- W2506460219 title "Management of Patient Samples and Specimens" @default.
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- W2506460219 doi "https://doi.org/10.1016/b978-0-12-382167-6.00035-7" @default.
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