FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2506570981> ?p ?o ?g. }

• W2506570981 endingPage "2247" @default.
• W2506570981 startingPage "2238" @default.
• W2506570981 abstract "Kupffer cells are the resident macrophages in the liver. They are located in hepatic sinusoid, which allows them to remove foreign materials, pathogens, and apoptotic cells efficiently. Activated Kupffer cells secrete various mediators, including cytokines and chemokines, to initiate immune responses, inflammation, or recruitment of other liver cells. Bile duct ligation (BDL) surgery in rodents is often studied as an animal model of cholestatic liver disease, characterized by obstruction of bile flow. BDL mice show altered functional activities of Kupffer cells compared with sham-operated mice, including elevated cytokine secretion and impaired bacterial clearance. Various mediators produced by other liver cells can regulate Kupffer cell activation, which suggest that Kupffer cells orchestrate with other liver cells to relay inflammatory signals and to maintain liver homeostasis during BDL-induced liver injury. Blocking or depletion of Kupffer cells, an approach for the treatment of liver diseases, has shown controversial implications. Procedures in Kupffer cell research have limitations and may produce various results in Kupffer cell research. It is important, however, to reveal underlying mechanisms of activation and functions of Kupffer cells, followed by hepatic inflammation and fibrosis. This review summarizes present Kupffer cell studies in cholestatic liver injury." @default.
• W2506570981 created "2016-08-23" @default.
• W2506570981 creator A5008932925 @default.
• W2506570981 creator A5010297487 @default.
• W2506570981 creator A5029205234 @default.
• W2506570981 creator A5030400303 @default.
• W2506570981 creator A5045220703 @default.
• W2506570981 creator A5050054185 @default.
• W2506570981 date "2016-09-01" @default.
• W2506570981 modified "2023-10-17" @default.
• W2506570981 title "Pathogenesis of Kupffer Cells in Cholestatic Liver Injury" @default.
• W2506570981 cites W1206320422 @default.
• W2506570981 cites W1490817952 @default.
• W2506570981 cites W1498290464 @default.
• W2506570981 cites W1521143540 @default.
• W2506570981 cites W1547680175 @default.
• W2506570981 cites W1556016535 @default.
• W2506570981 cites W1615683666 @default.
• W2506570981 cites W1638167482 @default.
• W2506570981 cites W1762925701 @default.
• W2506570981 cites W1775787040 @default.
• W2506570981 cites W1814471289 @default.
• W2506570981 cites W1930149436 @default.
• W2506570981 cites W1970136916 @default.
• W2506570981 cites W1974017543 @default.
• W2506570981 cites W1974035152 @default.
• W2506570981 cites W1975021657 @default.
• W2506570981 cites W1980636392 @default.
• W2506570981 cites W1981056356 @default.
• W2506570981 cites W1987142379 @default.
• W2506570981 cites W1989676489 @default.
• W2506570981 cites W1994231705 @default.
• W2506570981 cites W1995212212 @default.
• W2506570981 cites W1999258843 @default.
• W2506570981 cites W2000463136 @default.
• W2506570981 cites W2002356275 @default.
• W2506570981 cites W2002413439 @default.
• W2506570981 cites W2004142433 @default.
• W2506570981 cites W2005119615 @default.
• W2506570981 cites W2006953467 @default.
• W2506570981 cites W2010106434 @default.
• W2506570981 cites W2012962601 @default.
• W2506570981 cites W2017091300 @default.
• W2506570981 cites W2018286119 @default.
• W2506570981 cites W2020789652 @default.
• W2506570981 cites W2022313019 @default.
• W2506570981 cites W2023722200 @default.
• W2506570981 cites W2024706654 @default.
• W2506570981 cites W2028841855 @default.
• W2506570981 cites W2028912652 @default.
• W2506570981 cites W2029754162 @default.
• W2506570981 cites W2030936687 @default.
• W2506570981 cites W2031774854 @default.
• W2506570981 cites W2035704777 @default.
• W2506570981 cites W2038847295 @default.
• W2506570981 cites W2040318475 @default.
• W2506570981 cites W2040318556 @default.
• W2506570981 cites W2041885763 @default.
• W2506570981 cites W2047354583 @default.
• W2506570981 cites W2053391380 @default.
• W2506570981 cites W2057290552 @default.
• W2506570981 cites W2057576662 @default.
• W2506570981 cites W2058496317 @default.
• W2506570981 cites W2061213921 @default.
• W2506570981 cites W2062250771 @default.
• W2506570981 cites W2065833808 @default.
• W2506570981 cites W2067761476 @default.
• W2506570981 cites W2070855360 @default.
• W2506570981 cites W2070978905 @default.
• W2506570981 cites W2071840858 @default.
• W2506570981 cites W2073467203 @default.
• W2506570981 cites W2075950996 @default.
• W2506570981 cites W2077529924 @default.
• W2506570981 cites W2079684286 @default.
• W2506570981 cites W2080340658 @default.
• W2506570981 cites W2080857154 @default.
• W2506570981 cites W2081536518 @default.
• W2506570981 cites W2083968594 @default.
• W2506570981 cites W2098477897 @default.
• W2506570981 cites W2099673974 @default.
• W2506570981 cites W2107953386 @default.
• W2506570981 cites W2109646193 @default.
• W2506570981 cites W2113191326 @default.
• W2506570981 cites W2115116684 @default.
• W2506570981 cites W2117851005 @default.
• W2506570981 cites W2119330243 @default.
• W2506570981 cites W2134607150 @default.
• W2506570981 cites W2136354950 @default.
• W2506570981 cites W2138515833 @default.
• W2506570981 cites W2138915349 @default.
• W2506570981 cites W2140671259 @default.
• W2506570981 cites W2141408661 @default.
• W2506570981 cites W2142196461 @default.
• W2506570981 cites W2149641113 @default.
• W2506570981 cites W2153406260 @default.
• W2506570981 cites W2155772701 @default.
• W2506570981 cites W2156023352 @default.
• W2506570981 cites W2156263413 @default.

• next