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- W2506871621 abstract "In continuation of our pharmacological research on the in vivo induction or inhibition of the drug metabolizing enzymes system, a series of 32 derivatives of indole bearing aryl substituents in position 2 and 3 were investigated in regard to their effect on the in vivo synthesis of zoxazolamine hydroxylase in the young rat. Most fo the compounds examined proved to be inducers of this enzyme; however, as is the case with polycyclic carcinogens, the inducing activity was found to be significantly dependent on molecular structure." @default.
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- W2506871621 date "1975-01-01" @default.
- W2506871621 modified "2023-09-23" @default.
- W2506871621 title "Biochemical effects of 2-aryl- and 2,3-diarylindoles on the biosynthesis of zoxazolamine hydroxylase in rats." @default.
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