FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2507156929> ?p ?o ?g. }

• W2507156929 endingPage "e197" @default.
• W2507156929 startingPage "e187" @default.
• W2507156929 abstract "Epithelial-to-mesenchymal transition (EMT) is a dynamic process in the pathogenesis of urinary bladder cancer. Despite significant advancements in its diagnosis and treatment, the outcomes have more or less remained the same. In the present study, the expression of EMT markers was investigated to evaluate its prognostic significance in patients with non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).The present study was undertaken to examine the expression of EMT markers, including E-cadherin, N-cadherin, vimentin, Snail, Twist, Zeb, and Slug, on 28 bladder tumor tissues (15 cases of NMIBC and 13 of MIBC) using reverse transcription-polymerase chain reaction. Immunohistochemical (IHC) staining was performed to check the protein expression and localization of E-cadherin, N-cadherin, vimentin, Snail, and Slug.At the message level, reduced expression of E-cadherin correlated with gender (P = .004), enhanced expression of N-cadherin correlated with stage and age (P = .02, for both), and increased expression of EMT transcription factors correlated significantly with stage, grade, or age. Inverse correlation of reduced levels of E-cadherin were observed with new expression of N-cadherin (P = .001; Mann-Whitney U test) and vimentin (P = .001; Mann-Whitney U test). On IHC, novel expression of vimentin and N-cadherin was associated with enhanced expression of Snail and Slug (P = .005; Wilcoxon signed rank test).Molecular validation of the EMT marker profile proved to be a sensitive and an effective prognostic tool for objective and systematic investigation of EMT function in the pathogenesis of urinary bladder cancer. Nevertheless, further studies are required with a greater number of clinical samples." @default.
• W2507156929 created "2016-09-16" @default.
• W2507156929 creator A5008270484 @default.
• W2507156929 creator A5014548378 @default.
• W2507156929 creator A5017125035 @default.
• W2507156929 creator A5050168377 @default.
• W2507156929 creator A5075586289 @default.
• W2507156929 creator A5077997584 @default.
• W2507156929 date "2017-04-01" @default.
• W2507156929 modified "2023-09-27" @default.
• W2507156929 title "Epithelial-To-Mesenchymal Transition and Its Correlation With Clinicopathologic Features in Patients With Urothelial Carcinoma of the Bladder" @default.
• W2507156929 cites W1599695598 @default.
• W2507156929 cites W1741126710 @default.
• W2507156929 cites W2008299736 @default.
• W2507156929 cites W2012117840 @default.
• W2507156929 cites W2023089760 @default.
• W2507156929 cites W2025647419 @default.
• W2507156929 cites W2055082282 @default.
• W2507156929 cites W2076118448 @default.
• W2507156929 cites W2078134150 @default.
• W2507156929 cites W2082109120 @default.
• W2507156929 cites W2086040324 @default.
• W2507156929 cites W2102881172 @default.
• W2507156929 cites W2117490187 @default.
• W2507156929 cites W2128482295 @default.
• W2507156929 cites W2136979907 @default.
• W2507156929 cites W2150449422 @default.
• W2507156929 cites W2156662494 @default.
• W2507156929 cites W2159770815 @default.
• W2507156929 cites W2167198989 @default.
• W2507156929 cites W2171597083 @default.
• W2507156929 doi "https://doi.org/10.1016/j.clgc.2016.07.021" @default.
• W2507156929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27601277" @default.
• W2507156929 hasPublicationYear "2017" @default.
• W2507156929 type Work @default.
• W2507156929 sameAs 2507156929 @default.
• W2507156929 citedByCount "25" @default.
• W2507156929 countsByYear W25071569292017 @default.
• W2507156929 countsByYear W25071569292018 @default.
• W2507156929 countsByYear W25071569292019 @default.
• W2507156929 countsByYear W25071569292020 @default.
• W2507156929 countsByYear W25071569292021 @default.
• W2507156929 countsByYear W25071569292022 @default.
• W2507156929 countsByYear W25071569292023 @default.
• W2507156929 crossrefType "journal-article" @default.
• W2507156929 hasAuthorship W2507156929A5008270484 @default.
• W2507156929 hasAuthorship W2507156929A5014548378 @default.
• W2507156929 hasAuthorship W2507156929A5017125035 @default.
• W2507156929 hasAuthorship W2507156929A5050168377 @default.
• W2507156929 hasAuthorship W2507156929A5075586289 @default.
• W2507156929 hasAuthorship W2507156929A5077997584 @default.
• W2507156929 hasConcept C121608353 @default.
• W2507156929 hasConcept C126322002 @default.
• W2507156929 hasConcept C142724271 @default.
• W2507156929 hasConcept C143998085 @default.
• W2507156929 hasConcept C146357865 @default.
• W2507156929 hasConcept C147447768 @default.
• W2507156929 hasConcept C151730666 @default.
• W2507156929 hasConcept C204232928 @default.
• W2507156929 hasConcept C2778893926 @default.
• W2507156929 hasConcept C2779013556 @default.
• W2507156929 hasConcept C2780352672 @default.
• W2507156929 hasConcept C2780942790 @default.
• W2507156929 hasConcept C2781381752 @default.
• W2507156929 hasConcept C502942594 @default.
• W2507156929 hasConcept C71924100 @default.
• W2507156929 hasConcept C76419328 @default.
• W2507156929 hasConcept C86803240 @default.
• W2507156929 hasConceptScore W2507156929C121608353 @default.
• W2507156929 hasConceptScore W2507156929C126322002 @default.
• W2507156929 hasConceptScore W2507156929C142724271 @default.
• W2507156929 hasConceptScore W2507156929C143998085 @default.
• W2507156929 hasConceptScore W2507156929C146357865 @default.
• W2507156929 hasConceptScore W2507156929C147447768 @default.
• W2507156929 hasConceptScore W2507156929C151730666 @default.
• W2507156929 hasConceptScore W2507156929C204232928 @default.
• W2507156929 hasConceptScore W2507156929C2778893926 @default.
• W2507156929 hasConceptScore W2507156929C2779013556 @default.
• W2507156929 hasConceptScore W2507156929C2780352672 @default.
• W2507156929 hasConceptScore W2507156929C2780942790 @default.
• W2507156929 hasConceptScore W2507156929C2781381752 @default.
• W2507156929 hasConceptScore W2507156929C502942594 @default.
• W2507156929 hasConceptScore W2507156929C71924100 @default.
• W2507156929 hasConceptScore W2507156929C76419328 @default.
• W2507156929 hasConceptScore W2507156929C86803240 @default.
• W2507156929 hasIssue "2" @default.
• W2507156929 hasLocation W25071569291 @default.
• W2507156929 hasLocation W25071569292 @default.
• W2507156929 hasOpenAccess W2507156929 @default.
• W2507156929 hasPrimaryLocation W25071569291 @default.
• W2507156929 hasRelatedWork W2019771698 @default.
• W2507156929 hasRelatedWork W2035131746 @default.
• W2507156929 hasRelatedWork W2129377065 @default.
• W2507156929 hasRelatedWork W2187918977 @default.
• W2507156929 hasRelatedWork W2343878437 @default.
• W2507156929 hasRelatedWork W2507156929 @default.
• W2507156929 hasRelatedWork W2770634209 @default.
• W2507156929 hasRelatedWork W2789286023 @default.

• next