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• W2507383189 abstract "Fifth AACR International Conference on Frontiers in Cancer Prevention Research, Nov 12-15, 2006A201 We used data from a population-based case-control study conducted in western Washington during 1985-1999 including 1304 cases with endometrial cancer and 1779 controls to determine if the size of the increased risk of endometrial cancer among women with type II diabetes differs with respect to other endometrial cancer risk factors. History of type II diabetes was associated with endometrial cancer (odds ratio (OR): 1.9 95% confidence interval (CI): 1.4-2.7), more strongly among women with a recent diabetes diagnosis ( 5 years) (OR: 3.3 CI: 1.9-5.8 and OR: 1.5 CI: 1.0-2.2, respectively). Type II diabetes was associated with endometrial cancer among lean, overweight and obese women, and this association persisted after finer adjustment for body mass index (BMI) to control for residual confounding. Among women without hypertension, women with type II diabetes had a 1.3 fold elevation in risk relative to women without diabetes (CI: 0.7-2.2), whereas among women with hypertension, the corresponding odds ratio was 2.4 (CI: 1.5-3.7). The risk of endometrial cancer associated with type II diabetes appeared not to vary greatly with respect to use of unopposed estrogen therapy, smoking, age, race, education, or parity. Our results support the hypothesis that type II diabetes is associated with endometrial cancer irrespective of the presence of other risk factors for this disease." @default.
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• W2507383189 date "2006-12-01" @default.
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• W2507383189 title "Diabetes and endometrial cancer: An evaluation of the modifying effects of other known risk factors." @default.
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