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- W2507573772 abstract "Effects of strontium and lithium ion doping on the biological properties of bioactive glass (BAG) porous scaffolds have been checked in vitro and in vivo. BAG scaffolds were prepared by conventional glass melting route and subsequently, scaffolds were produced by evaporation of fugitive pore formers. After thorough physico-chemical and in vitro cell characterization, scaffolds were used for pre-clinical study. Soft and hard tissue formation in a rabbit femoral defect model after 2 and 4 months, were assessed using different tools. Histological observations showed excellent osseous tissue formation in Sr and Li + Sr scaffolds and moderate bone regeneration in Li scaffolds. Fluorochrome labeling studies showed wide regions of new bone formation in Sr and Li + Sr doped samples as compared to Li doped samples. SEM revealed abundant collagenous network and minimal or no interfacial gap between bone and implant in Sr and Li + Sr doped samples compared to Li doped samples. Micro CT of Li + Sr samples showed highest degree of peripheral cancellous tissue formation on periphery and cortical tissues inside implanted samples and vascularity among four compositions. Our findings suggest that addition of Sr and/or Li alters physico-chemical properties of BAG and promotes early stage in vivo osseointegration and bone remodeling that may offer new insight in bone tissue engineering." @default.
- W2507573772 created "2016-09-16" @default.
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- W2507573772 date "2016-09-08" @default.
- W2507573772 modified "2023-10-11" @default.
- W2507573772 title "Influence of single and binary doping of strontium and lithium on in vivo biological properties of bioactive glass scaffolds" @default.
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- W2507573772 cites W1970228722 @default.
- W2507573772 cites W1975265519 @default.
- W2507573772 cites W1981593427 @default.
- W2507573772 cites W1981612850 @default.
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- W2507573772 cites W1982414211 @default.
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- W2507573772 cites W1996710557 @default.
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- W2507573772 cites W2004315843 @default.
- W2507573772 cites W2006851263 @default.
- W2507573772 cites W2008274313 @default.
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- W2507573772 cites W2038555073 @default.
- W2507573772 cites W2039430435 @default.
- W2507573772 cites W2042450573 @default.
- W2507573772 cites W2047907147 @default.
- W2507573772 cites W2048766236 @default.
- W2507573772 cites W2055746941 @default.
- W2507573772 cites W2057255250 @default.
- W2507573772 cites W2061602582 @default.
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- W2507573772 cites W2065242899 @default.
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- W2507573772 cites W2080921228 @default.
- W2507573772 cites W2082602722 @default.
- W2507573772 cites W2089144492 @default.
- W2507573772 cites W2092654616 @default.
- W2507573772 cites W2093252878 @default.
- W2507573772 cites W2098799503 @default.
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- W2507573772 cites W2103232698 @default.
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- W2507573772 cites W2168890875 @default.
- W2507573772 cites W2169413646 @default.
- W2507573772 cites W2223937245 @default.
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- W2507573772 doi "https://doi.org/10.1038/srep32964" @default.
- W2507573772 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5015095" @default.
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