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- W2507771108 abstract "Allergic asthma is one of the well-known type 2 inflammatory diseases and is mainly mediated by T helper type 2 (Th2) cells (1). Environmental allergens such as house dust mite (HDM) causes lung eosinophilia (2). Followed by activation of lung epithelial cells and subsequent release of alarmins such as thymic stromal lymphopoietin (TSLP), IL-25 and IL-33 (3,4), dendritic cells (DCs) and B cells participate to prime naive CD4 T cells to differentiate them into Th2 effector cells to secrete Th2 cytokines (IL-4, IL-5 and IL-13) and to produce B cell-mediated humoral immune responses by Ig (immunoglobulin)-E (5,6)." @default.
- W2507771108 created "2016-09-16" @default.
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- W2507771108 date "2016-09-01" @default.
- W2507771108 modified "2023-09-26" @default.
- W2507771108 title "Snapshots of CD4+ T cell plasticity in the pathogenesis of allergic asthma" @default.
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- W2507771108 doi "https://doi.org/10.21037/jtd.2016.08.19" @default.
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