FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2508049555> ?p ?o ?g. }

• W2508049555 endingPage "135" @default.
• W2508049555 startingPage "131" @default.
• W2508049555 abstract "Neurogenic inflammation is a local inflammatory response that is driven by the peripheral release of neuropeptides from small diameter afferents which occurs in many organs including joints. The knee joint has a rich endocannabinoid system which has been shown to decrease acute synovitis. The aim of this study was to investigate the influence of joint afferents on leukocyte-endothelial interactions within the synovial microcirculation of mice and determine the role of endocannabinoids on this inflammatory response. Electrical, antidromic stimulation of the saphenous nerve decreased leukocyte rolling at the lowest frequency tested (0.5 Hz), while increasing leukocyte rolling at higher frequencies (2.0 and 5.0 Hz). The leukocyte rolling effect of nerve stimulation was completely abolished by pre-treating the knee with the vasoactive intestinal peptide antagonist VIP6–28; however, neither calcitonin gene related peptide nor substance P antagonism had an effect on this neurogenic inflammatory response. Treating knees with the endocannabinoid breakdown inhibitor URB597 completely blocked leukocyte rolling and this effect could be reversed with the non-canonical cannabinoid antagonist O-1918. These results provide evidence that antidromic stimulation of the mouse saphenous nerve promotes leukocyte rolling within the synovial microcirculation, and that endocannabinoids can attenuate this neurogenic inflammatory response." @default.
• W2508049555 created "2016-09-16" @default.
• W2508049555 creator A5004167898 @default.
• W2508049555 creator A5062891921 @default.
• W2508049555 creator A5078690094 @default.
• W2508049555 date "2017-08-01" @default.
• W2508049555 modified "2023-10-12" @default.
• W2508049555 title "Endocannabinoids inhibit neurogenic inflammation in murine joints by a non-canonical cannabinoid receptor mechanism" @default.
• W2508049555 cites W1508109586 @default.
• W2508049555 cites W1582311201 @default.
• W2508049555 cites W1679893116 @default.
• W2508049555 cites W1963796297 @default.
• W2508049555 cites W1969338731 @default.
• W2508049555 cites W1973525857 @default.
• W2508049555 cites W1974889608 @default.
• W2508049555 cites W1985648904 @default.
• W2508049555 cites W1987295999 @default.
• W2508049555 cites W1987913921 @default.
• W2508049555 cites W1990519669 @default.
• W2508049555 cites W1992499163 @default.
• W2508049555 cites W1995901113 @default.
• W2508049555 cites W2008612271 @default.
• W2508049555 cites W2010506344 @default.
• W2508049555 cites W2020475666 @default.
• W2508049555 cites W2024698877 @default.
• W2508049555 cites W2024956957 @default.
• W2508049555 cites W2029769928 @default.
• W2508049555 cites W2041519991 @default.
• W2508049555 cites W2047789754 @default.
• W2508049555 cites W2048835808 @default.
• W2508049555 cites W2054697305 @default.
• W2508049555 cites W2060979804 @default.
• W2508049555 cites W2072790756 @default.
• W2508049555 cites W2085448060 @default.
• W2508049555 cites W2088293679 @default.
• W2508049555 cites W2108130675 @default.
• W2508049555 cites W2110205870 @default.
• W2508049555 cites W2125311446 @default.
• W2508049555 cites W2166576741 @default.
• W2508049555 cites W4241363254 @default.
• W2508049555 doi "https://doi.org/10.1016/j.npep.2016.08.007" @default.
• W2508049555 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27567396" @default.
• W2508049555 hasPublicationYear "2017" @default.
• W2508049555 type Work @default.
• W2508049555 sameAs 2508049555 @default.
• W2508049555 citedByCount "9" @default.
• W2508049555 countsByYear W25080495552017 @default.
• W2508049555 countsByYear W25080495552018 @default.
• W2508049555 countsByYear W25080495552019 @default.
• W2508049555 countsByYear W25080495552020 @default.
• W2508049555 countsByYear W25080495552022 @default.
• W2508049555 crossrefType "journal-article" @default.
• W2508049555 hasAuthorship W2508049555A5004167898 @default.
• W2508049555 hasAuthorship W2508049555A5062891921 @default.
• W2508049555 hasAuthorship W2508049555A5078690094 @default.
• W2508049555 hasConcept C118303440 @default.
• W2508049555 hasConcept C126322002 @default.
• W2508049555 hasConcept C134018914 @default.
• W2508049555 hasConcept C148001335 @default.
• W2508049555 hasConcept C170493617 @default.
• W2508049555 hasConcept C24998067 @default.
• W2508049555 hasConcept C2776089194 @default.
• W2508049555 hasConcept C2776158853 @default.
• W2508049555 hasConcept C2776533618 @default.
• W2508049555 hasConcept C2776885963 @default.
• W2508049555 hasConcept C2776914184 @default.
• W2508049555 hasConcept C2780871563 @default.
• W2508049555 hasConcept C46721173 @default.
• W2508049555 hasConcept C70471684 @default.
• W2508049555 hasConcept C71924100 @default.
• W2508049555 hasConcept C98274493 @default.
• W2508049555 hasConceptScore W2508049555C118303440 @default.
• W2508049555 hasConceptScore W2508049555C126322002 @default.
• W2508049555 hasConceptScore W2508049555C134018914 @default.
• W2508049555 hasConceptScore W2508049555C148001335 @default.
• W2508049555 hasConceptScore W2508049555C170493617 @default.
• W2508049555 hasConceptScore W2508049555C24998067 @default.
• W2508049555 hasConceptScore W2508049555C2776089194 @default.
• W2508049555 hasConceptScore W2508049555C2776158853 @default.
• W2508049555 hasConceptScore W2508049555C2776533618 @default.
• W2508049555 hasConceptScore W2508049555C2776885963 @default.
• W2508049555 hasConceptScore W2508049555C2776914184 @default.
• W2508049555 hasConceptScore W2508049555C2780871563 @default.
• W2508049555 hasConceptScore W2508049555C46721173 @default.
• W2508049555 hasConceptScore W2508049555C70471684 @default.
• W2508049555 hasConceptScore W2508049555C71924100 @default.
• W2508049555 hasConceptScore W2508049555C98274493 @default.
• W2508049555 hasFunder F4320319950 @default.
• W2508049555 hasLocation W25080495551 @default.
• W2508049555 hasLocation W25080495552 @default.
• W2508049555 hasOpenAccess W2508049555 @default.
• W2508049555 hasPrimaryLocation W25080495551 @default.
• W2508049555 hasRelatedWork W1492609381 @default.
• W2508049555 hasRelatedWork W2044311961 @default.
• W2508049555 hasRelatedWork W2110308985 @default.
• W2508049555 hasRelatedWork W2129223461 @default.
• W2508049555 hasRelatedWork W2201563430 @default.
• W2508049555 hasRelatedWork W2417206429 @default.

• next