Matches in SemOpenAlex for { <https://semopenalex.org/work/W2508358294> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2508358294 abstract "Introduction: The aim of this study was to evaluate serum levels and urinary excretion of neutrophil-gelatinase associated lipocalin (respectively sNGAL and uNGAL) and urinary excretion of Cathepsin L (uCathL) in children with type 1 diabetes mellitus (DM1) who presented normoalbuminuria and the estimated glomerular filtration rate (eGFR) above 90 mL/min/1.73 m 2. Material and methods: The study group consisted of 63 children with a diabetes duration of 5.16 ± 3.39 years. The degree of albuminuria was based on urine albumin-to-creatinine ratio (ACR), while eGFR was based on serum cystatin C. Glomerular hyperfiltration (GH) was defined as an eGFR value above 135 mL/min/1.73 m 2. Results: Children with DM1 showed significantly higher concentrations of uNGAL, and lower sNGAL and uCathL. Significant changes of uNGAL and uCathL levels were even found in children without GH and with optimal glycaemic control (HbA 1c < 7.5%). Positive correlations between uNGAL, ACR and eGFR were shown, as well as between uCathL and eGFR. Conclusions: Significant changes in the concentration of markers of early kidney injury: sNGAL, uNGAL, and uCathL, can occur in children with DM1 and normoalbuminuria. The changes of uNGAL and uCathL can be even found in children without GH and with optimal gly- caemic control. The earliest signs of diabetic kidney dysfunction seem to result from tubular damage. (Endokrynol Pol 2014; 65 (6): 479-484)" @default.
- W2508358294 created "2016-09-16" @default.
- W2508358294 creator A5013469700 @default.
- W2508358294 creator A5040831327 @default.
- W2508358294 creator A5042150121 @default.
- W2508358294 creator A5060312194 @default.
- W2508358294 creator A5088855390 @default.
- W2508358294 date "2014-01-01" @default.
- W2508358294 modified "2023-09-24" @default.
- W2508358294 title "Neutrophil gelatinase-associated lipocalin and Cathepsin L as early predictors of kidney dysfunction in children with type 1 diabetes Lipokaina związana z żelatynazą neutrofilii i katepsyna L jako wczesne markery uszkodzenia nerek u dzieci z cukrzycą typu 1" @default.
- W2508358294 cites W1887718823 @default.
- W2508358294 cites W1964092586 @default.
- W2508358294 cites W1985090118 @default.
- W2508358294 cites W2000130658 @default.
- W2508358294 cites W2024229249 @default.
- W2508358294 cites W2027458711 @default.
- W2508358294 cites W2037795169 @default.
- W2508358294 cites W2040725678 @default.
- W2508358294 cites W2044757792 @default.
- W2508358294 cites W2046383629 @default.
- W2508358294 cites W2049428559 @default.
- W2508358294 cites W2077201010 @default.
- W2508358294 cites W2089664023 @default.
- W2508358294 cites W2093917807 @default.
- W2508358294 cites W2098530238 @default.
- W2508358294 cites W2103314755 @default.
- W2508358294 cites W2105525777 @default.
- W2508358294 cites W2126843907 @default.
- W2508358294 cites W2127885325 @default.
- W2508358294 cites W2131505504 @default.
- W2508358294 cites W2151678228 @default.
- W2508358294 cites W2152277167 @default.
- W2508358294 cites W2169392626 @default.
- W2508358294 cites W2395800284 @default.
- W2508358294 cites W2398229404 @default.
- W2508358294 cites W2405703114 @default.
- W2508358294 cites W26589038 @default.
- W2508358294 hasPublicationYear "2014" @default.
- W2508358294 type Work @default.
- W2508358294 sameAs 2508358294 @default.
- W2508358294 citedByCount "0" @default.
- W2508358294 crossrefType "journal-article" @default.
- W2508358294 hasAuthorship W2508358294A5013469700 @default.
- W2508358294 hasAuthorship W2508358294A5040831327 @default.
- W2508358294 hasAuthorship W2508358294A5042150121 @default.
- W2508358294 hasAuthorship W2508358294A5060312194 @default.
- W2508358294 hasAuthorship W2508358294A5088855390 @default.
- W2508358294 hasConcept C10146269 @default.
- W2508358294 hasConcept C126322002 @default.
- W2508358294 hasConcept C126894567 @default.
- W2508358294 hasConcept C134018914 @default.
- W2508358294 hasConcept C159641895 @default.
- W2508358294 hasConcept C2776174234 @default.
- W2508358294 hasConcept C2780091579 @default.
- W2508358294 hasConcept C2780306776 @default.
- W2508358294 hasConcept C2781203188 @default.
- W2508358294 hasConcept C555293320 @default.
- W2508358294 hasConcept C71924100 @default.
- W2508358294 hasConcept C90924648 @default.
- W2508358294 hasConceptScore W2508358294C10146269 @default.
- W2508358294 hasConceptScore W2508358294C126322002 @default.
- W2508358294 hasConceptScore W2508358294C126894567 @default.
- W2508358294 hasConceptScore W2508358294C134018914 @default.
- W2508358294 hasConceptScore W2508358294C159641895 @default.
- W2508358294 hasConceptScore W2508358294C2776174234 @default.
- W2508358294 hasConceptScore W2508358294C2780091579 @default.
- W2508358294 hasConceptScore W2508358294C2780306776 @default.
- W2508358294 hasConceptScore W2508358294C2781203188 @default.
- W2508358294 hasConceptScore W2508358294C555293320 @default.
- W2508358294 hasConceptScore W2508358294C71924100 @default.
- W2508358294 hasConceptScore W2508358294C90924648 @default.
- W2508358294 hasLocation W25083582941 @default.
- W2508358294 hasOpenAccess W2508358294 @default.
- W2508358294 hasPrimaryLocation W25083582941 @default.
- W2508358294 hasRelatedWork W1536042669 @default.
- W2508358294 hasRelatedWork W2044757792 @default.
- W2508358294 hasRelatedWork W2056787034 @default.
- W2508358294 hasRelatedWork W2067141598 @default.
- W2508358294 hasRelatedWork W2087528956 @default.
- W2508358294 hasRelatedWork W2100891309 @default.
- W2508358294 hasRelatedWork W2140634915 @default.
- W2508358294 hasRelatedWork W2323334317 @default.
- W2508358294 hasRelatedWork W2391464279 @default.
- W2508358294 hasRelatedWork W2531974717 @default.
- W2508358294 hasRelatedWork W2560848758 @default.
- W2508358294 hasRelatedWork W2885926053 @default.
- W2508358294 hasRelatedWork W2971226559 @default.
- W2508358294 hasRelatedWork W3028717733 @default.
- W2508358294 hasRelatedWork W3037396089 @default.
- W2508358294 hasRelatedWork W3039106269 @default.
- W2508358294 hasRelatedWork W3047848986 @default.
- W2508358294 hasRelatedWork W3109850150 @default.
- W2508358294 hasRelatedWork W3183060605 @default.
- W2508358294 hasRelatedWork W3188319801 @default.
- W2508358294 isParatext "false" @default.
- W2508358294 isRetracted "false" @default.
- W2508358294 magId "2508358294" @default.
- W2508358294 workType "article" @default.