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- W2508587374 abstract "Asthma is a chronic inflammatory disease by which, about 300 million people are affected worldwide. Response of most of asthmatic individuals is well to the currently available treatments of inhaled corticosteroids and beta-adrenergic agonists, however, 5–10% who has severe disease responds poorly. Addressing these challenges requires identification of novel drugs, development of non-invasive and cost effective methods, to select the most appropriate therapeutic option for asthma is complications caused by leukotriene, which is responsible for most of the deleterious effect of disease. This study has investigated the effect of naturally occurring compound limonene on 5-lipoxygenase encoded by ALOX5 in humans. It is an enzyme that converts essential fatty acids into leukotreine." @default.
- W2508587374 created "2016-09-16" @default.
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- W2508587374 date "2016-03-01" @default.
- W2508587374 modified "2023-10-04" @default.
- W2508587374 title "Structural and functional annotation of human ALOX-5" @default.
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- W2508587374 doi "https://doi.org/10.1109/bsb.2016.7552146" @default.
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