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- W2508937240 abstract "Immobilisation is known to be a risk factor for thromboembolic events and the management of ankle fractures often involves immobilisation of the fracture in a below knee cast. Recent literature has found a 5% rate of subclinical deep vein thrombosis (DVT) and suggested thromboembolic prophylaxis is not required. This study involved all adult patients with isolated ankle fractures presenting to a district general hospital orthopaedic department over a 6 month period. This included patients undergoing internal fixation as well as non-operative management. A 3 to 7 month follow-up was performed to assess the incidence of clinical DVT or pulmonary embolism (PE) proven using Doppler imaging, venogram, and computed tomography pulmonary angiography. 119 patients met the entry criteria and, of these, 3 patients developed DVT and 2 patients presented with pulmonary embolus. 15 patients in the study were taking aspirin (75–300 mg daily) during their cast immobilisation and 1 patient was taking warfarin. None of these patients developed a thromboembolic complication. 4.8% of patients not taking aspirin or warfarin experienced a thromboembolic complication. This study demonstrates a relatively high incidence of symptomatic thromboembolism following ankle fractures in the absence of prophylaxis. Previous studies have found aspirin to be an effective method of prophylaxis following hip fractures and total hip arthroplasty. We recommend that thromboembolism prophylaxis is necessary following ankle fractures and suggest that aspirin may be an economical option. Larger studies are needed to evaluate the role of aspirin in this setting." @default.
- W2508937240 created "2016-09-16" @default.
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- W2508937240 date "2011-01-01" @default.
- W2508937240 modified "2023-09-27" @default.
- W2508937240 title "THROMBOEMBOLIC EVENTS FOLLOWING ANKLE FRACTURE – DO WE NEED PROPHYLAXIS?" @default.
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