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• W2508945923 abstract "Type 1 diabetes mellitus (T1DM) is characterized by absolute insulin deficiency, primarily due to autoimmune-related destruction of pancreatic islet cells. It is usually diagnosed in children and young adults but can occur at any age. The rate of s-cell death is variable and individuals are usually clinically symptomatic when nearly 70–80 % of pancreatic s cell mass is depleted. Treatment with exogenous insulin is lifesaving and ensures survival. Globally, the prevalence of T1DM is growing at approximately 3 % per year (Fig. 5.1). Incidence rates show a wide geographic variation and of the estimated 497,100 children worldwide with T1DM, 26 % live in Northern Europe, followed by 22 % in North America and the Caribbean. In the last decade, rising incidence has been observed in parts of India, Middle East, and sub-Saharan Africa. The global increase in the numbers of individuals diagnosed with T1DM therefore has implications both for health-care resources and cost of management and places a greater demand on diabetologists, diabetes specialist nurses, dieticians, and primary care health-care professionals." @default.
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• W2508945923 date "2016-01-01" @default.
• W2508945923 modified "2023-09-28" @default.
• W2508945923 title "Insulin Management in Type 1 Diabetes" @default.
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• W2508945923 doi "https://doi.org/10.1007/978-3-319-10939-8_5" @default.
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