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- W2509091059 abstract "Introduction Patient specific plan verification becomes necessary in the advent of complex treatment delivery options with current linear accelerator technology. Purpose To use a patient-specific end-to-end quality assurance approach for plan verification and overall accuracy evaluation of a Volumetric Modulated Arc Therapy (VMAT) irradiation. Materials and methods Patient CT-scans were used to construct a phantom reproducing the patient anatomy in terms of external surface and bone structures using 3D-printing technology. The phantom was filled with a polymer-gel dosimeter and utilized to accurately reproduce every link in the treatment chain and irradiated using a 6 MV flattening filter free (fff) Elekta Versa linear accelerator. Upon irradiation, the phantom was MRI-scanned using a specially designed T2 pulse sequence and T2-maps were converted to 3D relative dose measurements. MR-images were imported to Monaco-TPS and co-registered to patient CT-images. TPS dose calculations were exported and used for dose comparison with measurements in an independent software. Results Radiation-induced polymerization area was clearly evident in the T2-images and found to coincide to the high-dose target area while organs at risk (OARs) were adequately spared in agreement with the TPS dose distribution. In addition, a quantitative evaluation was performed by comparing measured and TPS-calculated 3D dose-maps in terms of dose distributions, gamma index maps and Dose Volume Histogram (DVH) indices clinically used for plan evaluation and acceptance. Conclusion A patient-specific plan verification method offering the unique characteristic of providing 3D-dose distribution measurements in patient anatomy, including DVHs was implemented and revealed accurate delivery of the VMAT plan." @default.
- W2509091059 created "2016-09-16" @default.
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- W2509091059 date "2016-09-01" @default.
- W2509091059 modified "2023-09-27" @default.
- W2509091059 title "Patient specific plan verification of a VMAT plan using 3D polymer Gel dosimeter in a phantom reproducing patient anatomy" @default.
- W2509091059 doi "https://doi.org/10.1016/j.ejmp.2016.07.244" @default.
- W2509091059 hasPublicationYear "2016" @default.
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