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- W2509130340 abstract "Abstract In this work, the novel silica/polydimethylsiloxane/calcium phosphate composites (70%Si20%PDMS10%CaP and 60%Si20%PDMS20%CaP) were prepared in the sol–gel process combined with micromolding technique at room temperature. The self-formation rate of carbonate hydroxyapatite on the composites surface was examined under in vitro biomimetic conditions. Results showed the progressive increase in the surface mineralisation ability for 70%Si20%PDMS10%CaP composite and the retarded initial mineralisation promotion for the 60%Si20%PDMS20%CaP composite. In contrast, model drug release (doxorubicin) form the 60%Si20%PDMS20%CaP was slower compared to 70%Si20%PDMS10%CaP composite. This low temperature sol–gel micromolding process may lead to novel silica/polydimethylsiloxane/calcium phosphate composites with potential application as smart filling scaffolds in bone surgery with the possible loading of drug molecules." @default.
- W2509130340 created "2016-09-16" @default.
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- W2509130340 date "2016-12-01" @default.
- W2509130340 modified "2023-09-27" @default.
- W2509130340 title "Bioactive monolithic composites of silica/polydimethylsiloxane/calcium phosphate obtained at room temperature in sol–gel micromolding technique" @default.
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- W2509130340 doi "https://doi.org/10.1016/j.matlet.2016.08.063" @default.
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