Matches in SemOpenAlex for { <https://semopenalex.org/work/W2509284908> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2509284908 abstract "Migration of leucocytes into sites of into lamination and to phagocytose damaged cells and invading microorganisms is an immunological reaction of paramount importance. The circulating blood monocytes together with tissue macrophages and blood neutrophils are the cells which carry out this phagocytic function. Studies on different aspects of the locomotion of human blood monocytes are presented in this thesis. The neutrophils and the non-adherent mononuclear cells from human peripheral blood were also used in some experiments. Studies on monocytes were greatly hampered in the past because of the difficulties in obtaining purified preparations of the cells, Several procedures were tried in the present study, most of which for one reason or another, were unsatisfactory. The BHK microexudate method produced a considerably higher yield of purified populations of monocytes in suspension and was ultimately selected for subsequent studies. The responses of human blood monocytes to chemotactic factors were studied using an assay of morphological polarisation. Changes in cell morphology from a spherical to a polarised configuration which occurred within a few minutes of adding a chemotactic factor, were scored after incubating the cells in suspension followed by fixation with glutaraldehyde. Polarisation is the initial event in locomotion and can be scored accurately as has been shown in neutrophils. In contrast to neutrophils where more than 90% cells in a population can respond towards the formylated peptide FMLP, only 60 or so percent of the blood monocytes can do so. The rest of the cells do not bear receptors for FMLP and hence can not respond. Monocytes showed distinct morphological shapes in different concentrations of FMLP. The cells were most polarised in 5 X 10-." @default.
- W2509284908 created "2016-09-16" @default.
- W2509284908 creator A5039863793 @default.
- W2509284908 date "1986-01-01" @default.
- W2509284908 modified "2023-09-23" @default.
- W2509284908 title "Studies on chemoattractant-induced polarisation and locomotion of human blood leucocytes" @default.
- W2509284908 hasPublicationYear "1986" @default.
- W2509284908 type Work @default.
- W2509284908 sameAs 2509284908 @default.
- W2509284908 citedByCount "1" @default.
- W2509284908 crossrefType "dissertation" @default.
- W2509284908 hasAuthorship W2509284908A5039863793 @default.
- W2509284908 hasConcept C137061746 @default.
- W2509284908 hasConcept C160448771 @default.
- W2509284908 hasConcept C170493617 @default.
- W2509284908 hasConcept C185592680 @default.
- W2509284908 hasConcept C202751555 @default.
- W2509284908 hasConcept C203014093 @default.
- W2509284908 hasConcept C2781184567 @default.
- W2509284908 hasConcept C2908647359 @default.
- W2509284908 hasConcept C3020437955 @default.
- W2509284908 hasConcept C42407357 @default.
- W2509284908 hasConcept C54166955 @default.
- W2509284908 hasConcept C55493867 @default.
- W2509284908 hasConcept C71924100 @default.
- W2509284908 hasConcept C86803240 @default.
- W2509284908 hasConcept C95444343 @default.
- W2509284908 hasConcept C99454951 @default.
- W2509284908 hasConceptScore W2509284908C137061746 @default.
- W2509284908 hasConceptScore W2509284908C160448771 @default.
- W2509284908 hasConceptScore W2509284908C170493617 @default.
- W2509284908 hasConceptScore W2509284908C185592680 @default.
- W2509284908 hasConceptScore W2509284908C202751555 @default.
- W2509284908 hasConceptScore W2509284908C203014093 @default.
- W2509284908 hasConceptScore W2509284908C2781184567 @default.
- W2509284908 hasConceptScore W2509284908C2908647359 @default.
- W2509284908 hasConceptScore W2509284908C3020437955 @default.
- W2509284908 hasConceptScore W2509284908C42407357 @default.
- W2509284908 hasConceptScore W2509284908C54166955 @default.
- W2509284908 hasConceptScore W2509284908C55493867 @default.
- W2509284908 hasConceptScore W2509284908C71924100 @default.
- W2509284908 hasConceptScore W2509284908C86803240 @default.
- W2509284908 hasConceptScore W2509284908C95444343 @default.
- W2509284908 hasConceptScore W2509284908C99454951 @default.
- W2509284908 hasLocation W25092849081 @default.
- W2509284908 hasOpenAccess W2509284908 @default.
- W2509284908 hasPrimaryLocation W25092849081 @default.
- W2509284908 hasRelatedWork W10813178 @default.
- W2509284908 hasRelatedWork W1485108829 @default.
- W2509284908 hasRelatedWork W1753179082 @default.
- W2509284908 hasRelatedWork W1772023380 @default.
- W2509284908 hasRelatedWork W1896125035 @default.
- W2509284908 hasRelatedWork W1975875802 @default.
- W2509284908 hasRelatedWork W2016357954 @default.
- W2509284908 hasRelatedWork W2094532029 @default.
- W2509284908 hasRelatedWork W2106611133 @default.
- W2509284908 hasRelatedWork W2118323960 @default.
- W2509284908 hasRelatedWork W2136682979 @default.
- W2509284908 hasRelatedWork W2142080413 @default.
- W2509284908 hasRelatedWork W2196177060 @default.
- W2509284908 hasRelatedWork W2396385145 @default.
- W2509284908 hasRelatedWork W2417844328 @default.
- W2509284908 hasRelatedWork W2790091710 @default.
- W2509284908 hasRelatedWork W289410327 @default.
- W2509284908 hasRelatedWork W3161754055 @default.
- W2509284908 hasRelatedWork W32353186 @default.
- W2509284908 hasRelatedWork W335975268 @default.
- W2509284908 isParatext "false" @default.
- W2509284908 isRetracted "false" @default.
- W2509284908 magId "2509284908" @default.
- W2509284908 workType "dissertation" @default.