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- W2509654045 abstract "Fishes inhabit the microberich aquatic environmen t, hence are constantly under the threat of being infected with the microbial pathogens. Nonspecific immune system of fish forms the first line of defense in protecting them from the invading pathogens. Toll� like receptors (TLRs) are important components of nonspecific immunity that play an essential role in the recognition of the pathogens based on pathogen associated molecular patterns (PAMPs) and in inducing the nonspecific immunity. TLR9 recognizes the unmethylated CpG DNA of bacteria and viruses. As the expression level of TLRs in a host is an indicator of its health status and its ability to defend the pathogen challenge, the aim of this study was to compare the tissuespe cific expression profiles of TLR9 mRNA in Danio rerio (zebra fish) that were healthy and experimentally exposed to Aeromonas hydrophila, a gramnegative bacterium as it has not been repor ted so far. Observations of the study shows that tissuespecifi c differential expression of TLR9 mRNA is present in skin, gill, brain, liver, intestine and kidney of zebra fish and it could be upregulated upon exposure (4 h) to Aeromonas hydrophila. A.UMA" @default.
- W2509654045 created "2016-09-16" @default.
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- W2509654045 date "2012-01-01" @default.
- W2509654045 modified "2023-09-24" @default.
- W2509654045 title "Expression Of Toll-Like Receptor9 (Tlr9) In Zebra Fish (Danio Rerio) Experimentally Exposed To Aeromonas Hydrophila" @default.
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