Matches in SemOpenAlex for { <https://semopenalex.org/work/W2509723471> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2509723471 endingPage "176" @default.
- W2509723471 startingPage "167" @default.
- W2509723471 abstract "Abstract Type 1 diabetes mellitus (T1DM) is a T cell mediated autoimmune disease. Vitamin D was found to suppress the incidence of diabetes when bind to its receptor (VDR), probably by suppressing T cell activations. Thus the VDR gene polymorphism may have an impact on pathophysiology of this disease. Since there was no consistent association between VDR polymorphisms and the risk of T1DM, this study aimed to investigate a VDR gene polymorphism in Sudanese children with T1DM. We examined the VDR gene Bsm1 (rs1544410), Apa1 (rs7975232), and Taq1 (rs731236) single nucleotide polymorphisms in 174 children with T1DM, and 56 children as control, and the association of these polymorphisms with the diabetic control. Among study patients, the majority (85.63%) of diabetic patients reported metabolically poor controlled (HbA1c > 8%). As compared with the control, patients with T1DM presented more commonly with Bsm1 B allele (p = 0.001; OR 0.283; 95% CI 0.131–0.609) and Taq1 T allele (p = 0.05; OR 2.429; 95% CI 1.073–5.496). Apa1 A allele was less common in patients with T1DM without statistical difference (p = 0.862; OR 1.085; 95% CI 0.546–2.156). Our study suggests that, Bsm1 and Taq1 polymorphisms of the VDR gene associated with the prevalence of T1DM." @default.
- W2509723471 created "2016-09-16" @default.
- W2509723471 creator A5010011909 @default.
- W2509723471 date "2016-10-01" @default.
- W2509723471 modified "2023-09-25" @default.
- W2509723471 title "Vitamin D receptor gene polymorphisms in Sudanese children with type 1 diabetes" @default.
- W2509723471 cites W1567147531 @default.
- W2509723471 cites W1990365334 @default.
- W2509723471 cites W2007022299 @default.
- W2509723471 cites W2009180025 @default.
- W2509723471 cites W2021264322 @default.
- W2509723471 cites W2052067908 @default.
- W2509723471 cites W2052255259 @default.
- W2509723471 cites W2061171498 @default.
- W2509723471 cites W2063914119 @default.
- W2509723471 cites W2150438260 @default.
- W2509723471 cites W2153770089 @default.
- W2509723471 cites W2164269357 @default.
- W2509723471 cites W2164976842 @default.
- W2509723471 cites W2171713711 @default.
- W2509723471 cites W2465369226 @default.
- W2509723471 cites W391599721 @default.
- W2509723471 doi "https://doi.org/10.3934/genet.2016.3.167" @default.
- W2509723471 hasPublicationYear "2016" @default.
- W2509723471 type Work @default.
- W2509723471 sameAs 2509723471 @default.
- W2509723471 citedByCount "10" @default.
- W2509723471 countsByYear W25097234712019 @default.
- W2509723471 countsByYear W25097234712020 @default.
- W2509723471 countsByYear W25097234712021 @default.
- W2509723471 countsByYear W25097234712023 @default.
- W2509723471 crossrefType "journal-article" @default.
- W2509723471 hasAuthorship W2509723471A5010011909 @default.
- W2509723471 hasBestOaLocation W25097234711 @default.
- W2509723471 hasConcept C104317684 @default.
- W2509723471 hasConcept C124490489 @default.
- W2509723471 hasConcept C126322002 @default.
- W2509723471 hasConcept C134018914 @default.
- W2509723471 hasConcept C135763542 @default.
- W2509723471 hasConcept C149737253 @default.
- W2509723471 hasConcept C153209595 @default.
- W2509723471 hasConcept C179639408 @default.
- W2509723471 hasConcept C180754005 @default.
- W2509723471 hasConcept C203014093 @default.
- W2509723471 hasConcept C2781232474 @default.
- W2509723471 hasConcept C2910068830 @default.
- W2509723471 hasConcept C54355233 @default.
- W2509723471 hasConcept C555293320 @default.
- W2509723471 hasConcept C71924100 @default.
- W2509723471 hasConcept C76252995 @default.
- W2509723471 hasConcept C86803240 @default.
- W2509723471 hasConceptScore W2509723471C104317684 @default.
- W2509723471 hasConceptScore W2509723471C124490489 @default.
- W2509723471 hasConceptScore W2509723471C126322002 @default.
- W2509723471 hasConceptScore W2509723471C134018914 @default.
- W2509723471 hasConceptScore W2509723471C135763542 @default.
- W2509723471 hasConceptScore W2509723471C149737253 @default.
- W2509723471 hasConceptScore W2509723471C153209595 @default.
- W2509723471 hasConceptScore W2509723471C179639408 @default.
- W2509723471 hasConceptScore W2509723471C180754005 @default.
- W2509723471 hasConceptScore W2509723471C203014093 @default.
- W2509723471 hasConceptScore W2509723471C2781232474 @default.
- W2509723471 hasConceptScore W2509723471C2910068830 @default.
- W2509723471 hasConceptScore W2509723471C54355233 @default.
- W2509723471 hasConceptScore W2509723471C555293320 @default.
- W2509723471 hasConceptScore W2509723471C71924100 @default.
- W2509723471 hasConceptScore W2509723471C76252995 @default.
- W2509723471 hasConceptScore W2509723471C86803240 @default.
- W2509723471 hasIssue "03" @default.
- W2509723471 hasLocation W25097234711 @default.
- W2509723471 hasOpenAccess W2509723471 @default.
- W2509723471 hasPrimaryLocation W25097234711 @default.
- W2509723471 hasRelatedWork W141873526 @default.
- W2509723471 hasRelatedWork W1568218321 @default.
- W2509723471 hasRelatedWork W2037727994 @default.
- W2509723471 hasRelatedWork W2125384752 @default.
- W2509723471 hasRelatedWork W2362507127 @default.
- W2509723471 hasRelatedWork W2383975610 @default.
- W2509723471 hasRelatedWork W2969452988 @default.
- W2509723471 hasRelatedWork W3007549705 @default.
- W2509723471 hasRelatedWork W4308058546 @default.
- W2509723471 hasRelatedWork W4385174596 @default.
- W2509723471 hasVolume "03" @default.
- W2509723471 isParatext "false" @default.
- W2509723471 isRetracted "false" @default.
- W2509723471 magId "2509723471" @default.
- W2509723471 workType "article" @default.