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- W2509944186 endingPage "71051" @default.
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- W2509944186 abstract "Management of advanced hepatocellular carcinoma (HCC), one of the most lethal cancers worldwide, has presented a therapeutic challenge over past decades. Most patients with advanced HCC and a low possibility of surgical resection have limited treatment options and no alternative but to accept local or palliative treatment. In the new era of cancer therapy, increasing numbers of molecular targeted agents (MTAs) have been applied in the treatment of advanced HCC. However, mono-targeted therapy has shown disappointing outcomes in disease control, primarily because of tumor heterogeneity and complex cell signal transduction. Because incapacitation of a single target is insufficient for cancer suppression, combination treatment for targeted therapy has been proposed and experimentally tested in several clinical trials. In this article, we review research studies aimed to enhance the efficacy of targeted therapy for HCC through combination strategies. Combination treatments involving targeted therapy for advanced HCC are compared and discussed." @default.
- W2509944186 created "2016-09-16" @default.
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- W2509944186 date "2016-09-10" @default.
- W2509944186 modified "2023-10-17" @default.
- W2509944186 title "Combination treatment including targeted therapy for advanced hepatocellular carcinoma" @default.
- W2509944186 cites W1472398560 @default.
- W2509944186 cites W1499466280 @default.
- W2509944186 cites W1527076593 @default.
- W2509944186 cites W1543790510 @default.
- W2509944186 cites W1601002325 @default.
- W2509944186 cites W1633413258 @default.
- W2509944186 cites W1853436861 @default.
- W2509944186 cites W1863396492 @default.
- W2509944186 cites W1919425510 @default.
- W2509944186 cites W1930892342 @default.
- W2509944186 cites W1960849084 @default.
- W2509944186 cites W1962634412 @default.
- W2509944186 cites W1964100554 @default.
- W2509944186 cites W1965309017 @default.
- W2509944186 cites W1970060716 @default.
- W2509944186 cites W1971837077 @default.
- W2509944186 cites W1975154077 @default.
- W2509944186 cites W1981827594 @default.
- W2509944186 cites W1985199927 @default.
- W2509944186 cites W1987073180 @default.
- W2509944186 cites W1994193851 @default.
- W2509944186 cites W1995811009 @default.
- W2509944186 cites W1996106353 @default.
- W2509944186 cites W1996229105 @default.
- W2509944186 cites W1997482254 @default.
- W2509944186 cites W2002784910 @default.
- W2509944186 cites W2009720434 @default.
- W2509944186 cites W2014062997 @default.
- W2509944186 cites W2016170717 @default.
- W2509944186 cites W2019218097 @default.
- W2509944186 cites W2019634979 @default.
- W2509944186 cites W2019837162 @default.
- W2509944186 cites W2028525116 @default.
- W2509944186 cites W2028667086 @default.
- W2509944186 cites W2037014044 @default.
- W2509944186 cites W2037536053 @default.
- W2509944186 cites W2037678476 @default.
- W2509944186 cites W2037794622 @default.
- W2509944186 cites W2037951556 @default.
- W2509944186 cites W2038625523 @default.
- W2509944186 cites W2041819279 @default.
- W2509944186 cites W2041993682 @default.
- W2509944186 cites W2044653695 @default.
- W2509944186 cites W2046068483 @default.
- W2509944186 cites W2051684210 @default.
- W2509944186 cites W2052009118 @default.
- W2509944186 cites W2064802372 @default.
- W2509944186 cites W2069076782 @default.
- W2509944186 cites W2072010297 @default.
- W2509944186 cites W2075426209 @default.
- W2509944186 cites W2079514180 @default.
- W2509944186 cites W2080663543 @default.
- W2509944186 cites W2081437435 @default.
- W2509944186 cites W2081673273 @default.
- W2509944186 cites W2081886885 @default.
- W2509944186 cites W2084740377 @default.
- W2509944186 cites W2085273836 @default.
- W2509944186 cites W2089580059 @default.
- W2509944186 cites W2089854934 @default.
- W2509944186 cites W2097623895 @default.
- W2509944186 cites W2100106896 @default.
- W2509944186 cites W2101431311 @default.
- W2509944186 cites W2102304606 @default.
- W2509944186 cites W2105127629 @default.
- W2509944186 cites W2105604834 @default.
- W2509944186 cites W2112716777 @default.
- W2509944186 cites W2113794558 @default.
- W2509944186 cites W2114752093 @default.
- W2509944186 cites W2115315624 @default.
- W2509944186 cites W2115450250 @default.
- W2509944186 cites W2118234018 @default.
- W2509944186 cites W2119427023 @default.
- W2509944186 cites W2120871118 @default.
- W2509944186 cites W2125763116 @default.
- W2509944186 cites W2129501325 @default.
- W2509944186 cites W2130210996 @default.
- W2509944186 cites W2132006978 @default.
- W2509944186 cites W2132215313 @default.
- W2509944186 cites W2135131549 @default.
- W2509944186 cites W2135530657 @default.
- W2509944186 cites W2137052325 @default.
- W2509944186 cites W2140587309 @default.