FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2510105370> ?p ?o ?g. }

• W2510105370 endingPage "e12926" @default.
• W2510105370 startingPage "e12926" @default.
• W2510105370 abstract "Proton pump inhibitors (PPIs) are commonly used as potent gastric acid secretion antagonists for gastro-esophageal disorders and their overall safety in patients with gastro-esophageal reflux disease (GERD) is considered to be good and they are well-tolerated. However, recent studies have suggested that PPIs may be a potential independent risk factor for cardiovascular adverse events. The aim of our meta-analysis was to examine the association between PPI monotherapy and cardiovascular events in patients with GERD.A literature search involved examination of relevant databases up to July 2015 including PubMed, Cochrane Library, EMBASE, and ClinicalTrial.gov, as well as selected randomized controlled trials (RCTs) reporting cardiovascular events with PPI exposure in GERD patients. In addition, the pooled risk ratio (RR) and heterogeneity were assessed based on a fixed effects model of the meta-analysis and the I2 statistic, respectively.Seventeen RCTs covering 7540 patients were selected. The pooled data suggested that the use of PPIs was associated with a 70% increased cardiovascular risk (RR=1.70, 95% CI: [1.13-2.56], P=.01, I2 =0%). Furthermore, higher risks of adverse cardiovascular events in the omeprazole subgroup (RR=3.17, 95% CI: [1.43-7.03], P=.004, I2 =25%) and long-term treatment subgroup (RR=2.33, 95% CI: [1.33-4.08], P=.003, I2 =0%) were found.PPI monotherapy can be a risk factor for cardiovascular adverse events. Omeprazole could significantly increase the risk of cardiovascular events and, so, should be used carefully." @default.
• W2510105370 created "2016-09-16" @default.
• W2510105370 creator A5000031528 @default.
• W2510105370 creator A5013575039 @default.
• W2510105370 creator A5018174872 @default.
• W2510105370 creator A5032168226 @default.
• W2510105370 creator A5034140400 @default.
• W2510105370 creator A5060386151 @default.
• W2510105370 creator A5066068373 @default.
• W2510105370 creator A5082632880 @default.
• W2510105370 date "2016-08-30" @default.
• W2510105370 modified "2023-10-06" @default.
• W2510105370 title "Proton pump inhibitor monotherapy and the risk of cardiovascular events in patients with gastro-esophageal reflux disease: a meta-analysis" @default.
• W2510105370 cites W1540782459 @default.
• W2510105370 cites W1563509041 @default.
• W2510105370 cites W1965890500 @default.
• W2510105370 cites W1998128185 @default.
• W2510105370 cites W2004298071 @default.
• W2510105370 cites W2005501262 @default.
• W2510105370 cites W2014468837 @default.
• W2510105370 cites W2025841048 @default.
• W2510105370 cites W2028495955 @default.
• W2510105370 cites W2035097434 @default.
• W2510105370 cites W2036174370 @default.
• W2510105370 cites W2037681348 @default.
• W2510105370 cites W2055970963 @default.
• W2510105370 cites W2057517836 @default.
• W2510105370 cites W2071521423 @default.
• W2510105370 cites W2076628090 @default.
• W2510105370 cites W2083059992 @default.
• W2510105370 cites W2090211537 @default.
• W2510105370 cites W2091429963 @default.
• W2510105370 cites W2093265279 @default.
• W2510105370 cites W2098923148 @default.
• W2510105370 cites W2101696161 @default.
• W2510105370 cites W2103481781 @default.
• W2510105370 cites W2104675861 @default.
• W2510105370 cites W2108267048 @default.
• W2510105370 cites W2110420172 @default.
• W2510105370 cites W2125271565 @default.
• W2510105370 cites W2128278469 @default.
• W2510105370 cites W2133861650 @default.
• W2510105370 cites W2134027168 @default.
• W2510105370 cites W2136960413 @default.
• W2510105370 cites W2140036464 @default.
• W2510105370 cites W2143742417 @default.
• W2510105370 cites W2143777566 @default.
• W2510105370 cites W2148154274 @default.
• W2510105370 cites W2153049285 @default.
• W2510105370 cites W2163641198 @default.
• W2510105370 cites W2302382872 @default.
• W2510105370 cites W2316582092 @default.
• W2510105370 cites W2402192287 @default.
• W2510105370 cites W2883081813 @default.
• W2510105370 cites W2967639622 @default.
• W2510105370 doi "https://doi.org/10.1111/nmo.12926" @default.
• W2510105370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27577963" @default.
• W2510105370 hasPublicationYear "2016" @default.
• W2510105370 type Work @default.
• W2510105370 sameAs 2510105370 @default.
• W2510105370 citedByCount "44" @default.
• W2510105370 countsByYear W25101053702017 @default.
• W2510105370 countsByYear W25101053702018 @default.
• W2510105370 countsByYear W25101053702019 @default.
• W2510105370 countsByYear W25101053702020 @default.
• W2510105370 countsByYear W25101053702021 @default.
• W2510105370 countsByYear W25101053702022 @default.
• W2510105370 countsByYear W25101053702023 @default.
• W2510105370 crossrefType "journal-article" @default.
• W2510105370 hasAuthorship W2510105370A5000031528 @default.
• W2510105370 hasAuthorship W2510105370A5013575039 @default.
• W2510105370 hasAuthorship W2510105370A5018174872 @default.
• W2510105370 hasAuthorship W2510105370A5032168226 @default.
• W2510105370 hasAuthorship W2510105370A5034140400 @default.
• W2510105370 hasAuthorship W2510105370A5060386151 @default.
• W2510105370 hasAuthorship W2510105370A5066068373 @default.
• W2510105370 hasAuthorship W2510105370A5082632880 @default.
• W2510105370 hasConcept C126322002 @default.
• W2510105370 hasConcept C168563851 @default.
• W2510105370 hasConcept C187960798 @default.
• W2510105370 hasConcept C197934379 @default.
• W2510105370 hasConcept C22130703 @default.
• W2510105370 hasConcept C2776478404 @default.
• W2510105370 hasConcept C2777014526 @default.
• W2510105370 hasConcept C2777498785 @default.
• W2510105370 hasConcept C2779134260 @default.
• W2510105370 hasConcept C2781025758 @default.
• W2510105370 hasConcept C43270747 @default.
• W2510105370 hasConcept C44249647 @default.
• W2510105370 hasConcept C50440223 @default.
• W2510105370 hasConcept C71924100 @default.
• W2510105370 hasConcept C82789193 @default.
• W2510105370 hasConcept C90924648 @default.
• W2510105370 hasConcept C95190672 @default.
• W2510105370 hasConceptScore W2510105370C126322002 @default.
• W2510105370 hasConceptScore W2510105370C168563851 @default.
• W2510105370 hasConceptScore W2510105370C187960798 @default.
• W2510105370 hasConceptScore W2510105370C197934379 @default.

• next