Matches in SemOpenAlex for { <https://semopenalex.org/work/W2510132551> ?p ?o ?g. }
- W2510132551 abstract "20-40% of patients with malignant tumors have one or more brain metastases in the course of their illness. Brain metastases are the first manifestation of cancer in 5-10%. Manifestations such as intracranial hypertension or focal neurologic deficits are seen in over 80% of patients with brain metastases. Uncertainty surrounds the treatment of patients with intracranial metastases, as the existing data are derived from trials with low levels of evidence.This article is based on a selective literature review and on the authors' own experience of 100 consecutive patients who underwent surgery at the Department of Neurosurgery at Ruhr University Bochum (RUB), Germany.Multimodal treatment enables successful surgery for an increasing number of patients with brain metastases. The modalities and goals of treatment are established for each patient individually by an interdisciplinary tumor board. Drug therapy is usually indicated. Surgical resection followed by stereotactic radiotherapy prolongs mean survival by 3-6 months and lowers the risk of recurrence from 40% to 12.5%. In the authors' own experience, even seriously ill patients can benefit from the resection of brain metastases. The 30-day morbidity was 29%, accounted for mainly by medical complications such as pulmonary embolism, renal failure, and sepsis.Through the close interdisciplinary collaboration of neurosurgeons, radiation oncologists, and medical oncologists, the symptomatic state and the prognosis of patients with brain metastases can be improved. Longer overall survival implies that further studies will have to pay special attention to the toxicity of treatment." @default.
- W2510132551 created "2016-09-16" @default.
- W2510132551 creator A5061037633 @default.
- W2510132551 creator A5064645745 @default.
- W2510132551 creator A5066640097 @default.
- W2510132551 date "2016-06-17" @default.
- W2510132551 modified "2023-10-16" @default.
- W2510132551 title "The Interdisciplinary Management of Brain Metastases" @default.
- W2510132551 cites W111475906 @default.
- W2510132551 cites W1546924549 @default.
- W2510132551 cites W1547875810 @default.
- W2510132551 cites W1577516527 @default.
- W2510132551 cites W1588530629 @default.
- W2510132551 cites W1965370740 @default.
- W2510132551 cites W1968124356 @default.
- W2510132551 cites W1968471842 @default.
- W2510132551 cites W1971460510 @default.
- W2510132551 cites W1973233831 @default.
- W2510132551 cites W1975501308 @default.
- W2510132551 cites W1996386623 @default.
- W2510132551 cites W1998430067 @default.
- W2510132551 cites W2009776759 @default.
- W2510132551 cites W2010105898 @default.
- W2510132551 cites W2011416964 @default.
- W2510132551 cites W2030900959 @default.
- W2510132551 cites W2034862317 @default.
- W2510132551 cites W2043764192 @default.
- W2510132551 cites W2047930883 @default.
- W2510132551 cites W2059215605 @default.
- W2510132551 cites W2075597732 @default.
- W2510132551 cites W2078763461 @default.
- W2510132551 cites W2082410073 @default.
- W2510132551 cites W2084859610 @default.
- W2510132551 cites W2101062860 @default.
- W2510132551 cites W2102635417 @default.
- W2510132551 cites W2127714076 @default.
- W2510132551 cites W2144907807 @default.
- W2510132551 cites W2149100644 @default.
- W2510132551 cites W2154025216 @default.
- W2510132551 cites W2155014512 @default.
- W2510132551 cites W2159776991 @default.
- W2510132551 cites W2161902281 @default.
- W2510132551 cites W2166271896 @default.
- W2510132551 cites W2166331688 @default.
- W2510132551 cites W2167243078 @default.
- W2510132551 cites W2186638557 @default.
- W2510132551 doi "https://doi.org/10.3238/arztebl.2016.0415" @default.
- W2510132551 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4939429" @default.
- W2510132551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27380757" @default.
- W2510132551 hasPublicationYear "2016" @default.
- W2510132551 type Work @default.
- W2510132551 sameAs 2510132551 @default.
- W2510132551 citedByCount "13" @default.
- W2510132551 countsByYear W25101325512017 @default.
- W2510132551 countsByYear W25101325512018 @default.
- W2510132551 countsByYear W25101325512019 @default.
- W2510132551 countsByYear W25101325512021 @default.
- W2510132551 countsByYear W25101325512023 @default.
- W2510132551 crossrefType "journal-article" @default.
- W2510132551 hasAuthorship W2510132551A5061037633 @default.
- W2510132551 hasAuthorship W2510132551A5064645745 @default.
- W2510132551 hasAuthorship W2510132551A5066640097 @default.
- W2510132551 hasBestOaLocation W25101325512 @default.
- W2510132551 hasConcept C121608353 @default.
- W2510132551 hasConcept C126322002 @default.
- W2510132551 hasConcept C12770488 @default.
- W2510132551 hasConcept C141071460 @default.
- W2510132551 hasConcept C144024400 @default.
- W2510132551 hasConcept C177713679 @default.
- W2510132551 hasConcept C2778164965 @default.
- W2510132551 hasConcept C2778384902 @default.
- W2510132551 hasConcept C2779013556 @default.
- W2510132551 hasConcept C2779903281 @default.
- W2510132551 hasConcept C2780387249 @default.
- W2510132551 hasConcept C36289849 @default.
- W2510132551 hasConcept C509974204 @default.
- W2510132551 hasConcept C513090587 @default.
- W2510132551 hasConcept C71924100 @default.
- W2510132551 hasConceptScore W2510132551C121608353 @default.
- W2510132551 hasConceptScore W2510132551C126322002 @default.
- W2510132551 hasConceptScore W2510132551C12770488 @default.
- W2510132551 hasConceptScore W2510132551C141071460 @default.
- W2510132551 hasConceptScore W2510132551C144024400 @default.
- W2510132551 hasConceptScore W2510132551C177713679 @default.
- W2510132551 hasConceptScore W2510132551C2778164965 @default.
- W2510132551 hasConceptScore W2510132551C2778384902 @default.
- W2510132551 hasConceptScore W2510132551C2779013556 @default.
- W2510132551 hasConceptScore W2510132551C2779903281 @default.
- W2510132551 hasConceptScore W2510132551C2780387249 @default.
- W2510132551 hasConceptScore W2510132551C36289849 @default.
- W2510132551 hasConceptScore W2510132551C509974204 @default.
- W2510132551 hasConceptScore W2510132551C513090587 @default.
- W2510132551 hasConceptScore W2510132551C71924100 @default.
- W2510132551 hasLocation W25101325511 @default.
- W2510132551 hasLocation W25101325512 @default.
- W2510132551 hasLocation W25101325513 @default.
- W2510132551 hasLocation W25101325514 @default.
- W2510132551 hasOpenAccess W2510132551 @default.
- W2510132551 hasPrimaryLocation W25101325511 @default.
- W2510132551 hasRelatedWork W124069250 @default.