Matches in SemOpenAlex for { <https://semopenalex.org/work/W2510134374> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2510134374 endingPage "436" @default.
- W2510134374 startingPage "430" @default.
- W2510134374 abstract "Migration of vascular smooth muscle cells (VSMCs) from the media to intima constitutes a critical step in the development of proliferative vascular diseases. To elucidate the regulatory mechanism of VSMCs motility, the roles of caldesmon (CaD) were investigated previously. CaD is an actin-binding protein dynamically regulating cytoskeleton structure. In this study, the potential role of CaD in mediating proliferation and motility of VSMCs were discussed. First, structural effect of CaD on cytoskeleton integrity was analyzed with CaD knock-down; second, the proliferation of VSMCs was measured in CaD knock-down and control cells; third, the specific role of CaD on VSMCs motilities was evaluated with in vitro migration and invasion assays. We found that CaD is an integral component to maintain cytoskeleton integrity of VSMCs. Our data indicated that CaD suppression does not show significant influence on VSMCs proliferation, but negatively modulates the motilities of VSMCs, and CaD depletion would significantly facilitate migration and invasion of VSMCs." @default.
- W2510134374 created "2016-09-16" @default.
- W2510134374 creator A5013950924 @default.
- W2510134374 creator A5035182816 @default.
- W2510134374 date "2016-01-01" @default.
- W2510134374 modified "2023-10-14" @default.
- W2510134374 title "The Influence of Caldesmon Suppression on Proliferation and Motilities of Vascular Smooth Muscle Cells" @default.
- W2510134374 cites W1534692597 @default.
- W2510134374 cites W1609692701 @default.
- W2510134374 cites W1780910759 @default.
- W2510134374 cites W1970429418 @default.
- W2510134374 cites W1996516396 @default.
- W2510134374 cites W1997941330 @default.
- W2510134374 cites W2012000549 @default.
- W2510134374 cites W2022835736 @default.
- W2510134374 cites W2028810337 @default.
- W2510134374 cites W2071580276 @default.
- W2510134374 cites W2139397108 @default.
- W2510134374 cites W2141832377 @default.
- W2510134374 cites W2144993485 @default.
- W2510134374 cites W2163802608 @default.
- W2510134374 cites W2171324002 @default.
- W2510134374 doi "https://doi.org/10.4236/jbise.2016.99038" @default.
- W2510134374 hasPublicationYear "2016" @default.
- W2510134374 type Work @default.
- W2510134374 sameAs 2510134374 @default.
- W2510134374 citedByCount "0" @default.
- W2510134374 crossrefType "journal-article" @default.
- W2510134374 hasAuthorship W2510134374A5013950924 @default.
- W2510134374 hasAuthorship W2510134374A5035182816 @default.
- W2510134374 hasBestOaLocation W25101343741 @default.
- W2510134374 hasConcept C125705527 @default.
- W2510134374 hasConcept C134018914 @default.
- W2510134374 hasConcept C142669718 @default.
- W2510134374 hasConcept C1491633281 @default.
- W2510134374 hasConcept C181199279 @default.
- W2510134374 hasConcept C2779360546 @default.
- W2510134374 hasConcept C2779395532 @default.
- W2510134374 hasConcept C29688787 @default.
- W2510134374 hasConcept C2992686903 @default.
- W2510134374 hasConcept C2993400109 @default.
- W2510134374 hasConcept C55493867 @default.
- W2510134374 hasConcept C58207958 @default.
- W2510134374 hasConcept C86803240 @default.
- W2510134374 hasConcept C95444343 @default.
- W2510134374 hasConceptScore W2510134374C125705527 @default.
- W2510134374 hasConceptScore W2510134374C134018914 @default.
- W2510134374 hasConceptScore W2510134374C142669718 @default.
- W2510134374 hasConceptScore W2510134374C1491633281 @default.
- W2510134374 hasConceptScore W2510134374C181199279 @default.
- W2510134374 hasConceptScore W2510134374C2779360546 @default.
- W2510134374 hasConceptScore W2510134374C2779395532 @default.
- W2510134374 hasConceptScore W2510134374C29688787 @default.
- W2510134374 hasConceptScore W2510134374C2992686903 @default.
- W2510134374 hasConceptScore W2510134374C2993400109 @default.
- W2510134374 hasConceptScore W2510134374C55493867 @default.
- W2510134374 hasConceptScore W2510134374C58207958 @default.
- W2510134374 hasConceptScore W2510134374C86803240 @default.
- W2510134374 hasConceptScore W2510134374C95444343 @default.
- W2510134374 hasIssue "09" @default.
- W2510134374 hasLocation W25101343741 @default.
- W2510134374 hasOpenAccess W2510134374 @default.
- W2510134374 hasPrimaryLocation W25101343741 @default.
- W2510134374 hasRelatedWork W1971766102 @default.
- W2510134374 hasRelatedWork W1999152177 @default.
- W2510134374 hasRelatedWork W2001709796 @default.
- W2510134374 hasRelatedWork W2006307965 @default.
- W2510134374 hasRelatedWork W2065666141 @default.
- W2510134374 hasRelatedWork W2113266085 @default.
- W2510134374 hasRelatedWork W2131939253 @default.
- W2510134374 hasRelatedWork W2170809835 @default.
- W2510134374 hasRelatedWork W2594707584 @default.
- W2510134374 hasRelatedWork W2611747722 @default.
- W2510134374 hasVolume "09" @default.
- W2510134374 isParatext "false" @default.
- W2510134374 isRetracted "false" @default.
- W2510134374 magId "2510134374" @default.
- W2510134374 workType "article" @default.