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- W2510144363 abstract "Euonymus alatus (E. alatus) is a medicinal plant used in some Asian countries for treating various conditions including cancer, hyperglycemia, and diabetic complications. This review outlines the phytochemistry and bioactivities of E. alatus related to antidiabetic actions. More than 100 chemical constituents have been isolated and identified from E. alatus , including flavonoids, terpenoids, steroids, lignans, cardenolides, phenolic acids, and alkaloids. Studies in vitro and in vivo have demonstrated the hypoglycemic activity of E. alatus extracts and its certain constituents. The hypoglycemic activity of E. alatus may be related to regulation of insulin signaling and insulin sensitivity, involving PPAR γ and aldose reductase pathways. Further studies on E. alatus and its bioactive compounds may help to develop new agents for treating diabetes and diabetic complications." @default.
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- W2510144363 date "2016-01-01" @default.
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- W2510144363 title "<i>Euonymus alatus</i>: A Review on Its Phytochemistry and Antidiabetic Activity" @default.
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- W2510144363 doi "https://doi.org/10.1155/2016/9425714" @default.
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