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- W2510165788 endingPage "7058" @default.
- W2510165788 startingPage "7058" @default.
- W2510165788 abstract "Colorectal cancer (CRC) is a type of cancer with high morbidity and mortality rates worldwide and has become a global health problem. The conventional radiotherapy and chemotherapy regimen for CRC not only has a low cure rate but also causes side effects. Many studies have shown that adequate intake of fruits and vegetables in the diet may have a protective effect on CRC occurrence, possibly due to the special biological protective effect of the phytochemicals in these foods. Numerous in vitro and in vivo studies have demonstrated that phytochemicals play strong antioxidant, anti-inflammatory and anti-cancer roles by regulating specific signaling pathways and molecular markers to inhibit the occurrence and development of CRC. This review summarizes the progress on CRC prevention using the phytochemicals sulforaphane, curcumin and resveratrol, and elaborates on the specific underlying mechanisms. Thus, we believe that phytochemicals might provide a novel therapeutic approach for CRC prevention, but future clinical studies are needed to confirm the specific preventive effect of phytochemicals on cancer." @default.
- W2510165788 created "2016-09-16" @default.
- W2510165788 creator A5008595700 @default.
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- W2510165788 creator A5031625599 @default.
- W2510165788 creator A5043932470 @default.
- W2510165788 creator A5091504056 @default.
- W2510165788 date "2016-01-01" @default.
- W2510165788 modified "2023-10-06" @default.
- W2510165788 title "Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms" @default.
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