Matches in SemOpenAlex for { <https://semopenalex.org/work/W2510177665> ?p ?o ?g. }
- W2510177665 endingPage "459" @default.
- W2510177665 startingPage "455" @default.
- W2510177665 abstract "Objective To examine the clinical results of a preoperative image-guided pulse-dose-rate brachytherapy (PDR-BT) in early stage cervical cancer. Materials/methods We examined the outcome of consecutive patients with early stage cervical cancer undergoing preoperative image-guided PDR-BT between 2004 and 2013 because of risk factors (lymphovascular embols and/or tumour > 2 cm). The objective was to deliver 60 Gy to 100% of the intermediate risk clinical target volume. Brachytherapy was followed, 6–8 weeks later, by a radical hysterectomy/bilateral salpingo-oophorectomy plus pelvic +/− para-aortic lymph node dissection. Patients with positive lymph nodes had postoperative chemoradiation. Results 77 patients met the above criteria of preoperative PDR-BT. On hysterectomy specimen, 54 (70.1%) presented a complete histological response. Four (5.2%) had a tumour residuum ⩾ 1 cm. Median follow-up was 46.8 months. 5-Year disease-free survival (DFS) rate was 84.4%. Only one local recurrence was observed. The presence of lymph nodal metastases, a tumour size > 3 cm and a brachytherapy/surgery time interval ⩾ 9 weeks correlated with a poorer DFS. Six postoperative complications were encountered (7.8%). Total reference air kerma correlated with late vaginal toxicity (p = 0.02). Conclusions A preoperative image-guided PDR-BT was safe and effective. Predictive factors for survival and toxicity were evidenced." @default.
- W2510177665 created "2016-09-16" @default.
- W2510177665 creator A5006937811 @default.
- W2510177665 creator A5007216769 @default.
- W2510177665 creator A5014829112 @default.
- W2510177665 creator A5023001652 @default.
- W2510177665 creator A5027613171 @default.
- W2510177665 creator A5038613943 @default.
- W2510177665 creator A5054031200 @default.
- W2510177665 creator A5068282558 @default.
- W2510177665 creator A5068492115 @default.
- W2510177665 creator A5073239916 @default.
- W2510177665 creator A5081179485 @default.
- W2510177665 creator A5082766465 @default.
- W2510177665 creator A5085510763 @default.
- W2510177665 date "2016-09-01" @default.
- W2510177665 modified "2023-10-16" @default.
- W2510177665 title "Preoperative image-guided brachytherapy in early stage cervical cancers" @default.
- W2510177665 cites W1971465280 @default.
- W2510177665 cites W1971881828 @default.
- W2510177665 cites W1977125071 @default.
- W2510177665 cites W1985283271 @default.
- W2510177665 cites W1987269690 @default.
- W2510177665 cites W1995699258 @default.
- W2510177665 cites W1998898748 @default.
- W2510177665 cites W1999267929 @default.
- W2510177665 cites W2008254357 @default.
- W2510177665 cites W2015544523 @default.
- W2510177665 cites W2016787080 @default.
- W2510177665 cites W2021957283 @default.
- W2510177665 cites W2048279859 @default.
- W2510177665 cites W2051206302 @default.
- W2510177665 cites W2070789376 @default.
- W2510177665 cites W2081977840 @default.
- W2510177665 cites W2088151214 @default.
- W2510177665 cites W2088897910 @default.
- W2510177665 cites W2090498460 @default.
- W2510177665 cites W2120405223 @default.
- W2510177665 cites W2122321342 @default.
- W2510177665 cites W2123297927 @default.
- W2510177665 cites W2134490068 @default.
- W2510177665 cites W2155153063 @default.
- W2510177665 cites W2173933403 @default.
- W2510177665 cites W2215628427 @default.
- W2510177665 cites W2320019843 @default.
- W2510177665 cites W4247169047 @default.
- W2510177665 doi "https://doi.org/10.1016/j.radonc.2016.07.003" @default.
- W2510177665 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27614680" @default.
- W2510177665 hasPublicationYear "2016" @default.
- W2510177665 type Work @default.
- W2510177665 sameAs 2510177665 @default.
- W2510177665 citedByCount "14" @default.
- W2510177665 countsByYear W25101776652017 @default.
- W2510177665 countsByYear W25101776652018 @default.
- W2510177665 countsByYear W25101776652020 @default.
- W2510177665 countsByYear W25101776652021 @default.
- W2510177665 countsByYear W25101776652022 @default.
- W2510177665 countsByYear W25101776652023 @default.
- W2510177665 crossrefType "journal-article" @default.
- W2510177665 hasAuthorship W2510177665A5006937811 @default.
- W2510177665 hasAuthorship W2510177665A5007216769 @default.
- W2510177665 hasAuthorship W2510177665A5014829112 @default.
- W2510177665 hasAuthorship W2510177665A5023001652 @default.
- W2510177665 hasAuthorship W2510177665A5027613171 @default.
- W2510177665 hasAuthorship W2510177665A5038613943 @default.
- W2510177665 hasAuthorship W2510177665A5054031200 @default.
- W2510177665 hasAuthorship W2510177665A5068282558 @default.
- W2510177665 hasAuthorship W2510177665A5068492115 @default.
- W2510177665 hasAuthorship W2510177665A5073239916 @default.
- W2510177665 hasAuthorship W2510177665A5081179485 @default.
- W2510177665 hasAuthorship W2510177665A5082766465 @default.
- W2510177665 hasAuthorship W2510177665A5085510763 @default.
- W2510177665 hasConcept C121608353 @default.
- W2510177665 hasConcept C126322002 @default.
- W2510177665 hasConcept C126838900 @default.
- W2510177665 hasConcept C141071460 @default.
- W2510177665 hasConcept C146357865 @default.
- W2510177665 hasConcept C151730666 @default.
- W2510177665 hasConcept C2775862295 @default.
- W2510177665 hasConcept C2777416452 @default.
- W2510177665 hasConcept C2778220009 @default.
- W2510177665 hasConcept C2779494336 @default.
- W2510177665 hasConcept C2780849966 @default.
- W2510177665 hasConcept C2910227796 @default.
- W2510177665 hasConcept C509974204 @default.
- W2510177665 hasConcept C71924100 @default.
- W2510177665 hasConcept C86803240 @default.
- W2510177665 hasConceptScore W2510177665C121608353 @default.
- W2510177665 hasConceptScore W2510177665C126322002 @default.
- W2510177665 hasConceptScore W2510177665C126838900 @default.
- W2510177665 hasConceptScore W2510177665C141071460 @default.
- W2510177665 hasConceptScore W2510177665C146357865 @default.
- W2510177665 hasConceptScore W2510177665C151730666 @default.
- W2510177665 hasConceptScore W2510177665C2775862295 @default.
- W2510177665 hasConceptScore W2510177665C2777416452 @default.
- W2510177665 hasConceptScore W2510177665C2778220009 @default.
- W2510177665 hasConceptScore W2510177665C2779494336 @default.
- W2510177665 hasConceptScore W2510177665C2780849966 @default.