FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2510180195> ?p ?o ?g. }

• W2510180195 endingPage "585" @default.
• W2510180195 startingPage "576" @default.
• W2510180195 abstract "Abstract Chronic lithium treatment effectively reduces behavioral phenotypes of mania in humans and rodents. The mechanisms by which lithium exerts these actions are poorly understood. Pre‐clinical and clinical evidence have implicated increased mesolimbic dopamine ( DA ) neurotransmission with mania. We used fast‐scan cyclic voltammetry to characterize changes in extracellular DA concentrations in the nucleus accumbens ( NA c) core evoked by 20 and 60 Hz electrical stimulation of the ventral tegmental area ( VTA ) in C57 BL 6/J mice treated either acutely or chronically with lithium. The effects of chronic lithium treatment on the availability of DA for release were assessed by depleting readily releasable DA using short inter‐train intervals, or administering d ‐amphetamine acutely to mobilize readily releasable DA . Chronic, but not acute, lithium treatment decreased the amplitude of DA responses in the NA c following 60 Hz pulse train stimulation. Neither lithium treatment altered the kinetics of DA release or reuptake. Chronic treatment did not impact the progressive reduction in the amplitude of DA responses when, using 20 or 60 Hz pulse trains, the VTA was stimulated every 6 s to deplete DA . Specifically, the amplitude of DA responses to 60 Hz pulse trains was initially reduced compared to control mice, but by the fifth pulse train, there was no longer a treatment effect. However, chronic lithium treatment attenuated d ‐amphetamine‐induced increases in DA responses to 20 Hz pulse trains stimulation. Our data suggest that long‐term administration of lithium may ameliorate mania phenotypes by normalizing the readily releasable DA pool in VTA axon terminals in the NA c. image Read the Editorial Highlight for this article on Page 520 ." @default.
• W2510180195 created "2016-09-16" @default.
• W2510180195 creator A5037853531 @default.
• W2510180195 creator A5051802152 @default.
• W2510180195 creator A5053701037 @default.
• W2510180195 creator A5085620061 @default.
• W2510180195 creator A5089659362 @default.
• W2510180195 date "2016-10-18" @default.
• W2510180195 modified "2023-10-04" @default.
• W2510180195 title "Chronic lithium treatment rectifies maladaptive dopamine release in the nucleus accumbens" @default.
• W2510180195 cites W1036203780 @default.
• W2510180195 cites W1558691576 @default.
• W2510180195 cites W1578789617 @default.
• W2510180195 cites W1658065850 @default.
• W2510180195 cites W1966004542 @default.
• W2510180195 cites W1969942100 @default.
• W2510180195 cites W1971712976 @default.
• W2510180195 cites W1973189506 @default.
• W2510180195 cites W1984267890 @default.
• W2510180195 cites W1989014374 @default.
• W2510180195 cites W1989396363 @default.
• W2510180195 cites W1993995078 @default.
• W2510180195 cites W1998137325 @default.
• W2510180195 cites W1998352623 @default.
• W2510180195 cites W2001812998 @default.
• W2510180195 cites W2004137994 @default.
• W2510180195 cites W2004264470 @default.
• W2510180195 cites W2018602168 @default.
• W2510180195 cites W2021092225 @default.
• W2510180195 cites W2021782736 @default.
• W2510180195 cites W2023509166 @default.
• W2510180195 cites W2024066498 @default.
• W2510180195 cites W2025998453 @default.
• W2510180195 cites W2027107708 @default.
• W2510180195 cites W2027639125 @default.
• W2510180195 cites W2030500089 @default.
• W2510180195 cites W2034375744 @default.
• W2510180195 cites W2037852648 @default.
• W2510180195 cites W2041219933 @default.
• W2510180195 cites W2049459393 @default.
• W2510180195 cites W2059115988 @default.
• W2510180195 cites W2062890107 @default.
• W2510180195 cites W2063627275 @default.
• W2510180195 cites W2064638344 @default.
• W2510180195 cites W2071825212 @default.
• W2510180195 cites W2073317842 @default.
• W2510180195 cites W2076218424 @default.
• W2510180195 cites W2083998651 @default.
• W2510180195 cites W2089484399 @default.
• W2510180195 cites W2089768018 @default.
• W2510180195 cites W2091990839 @default.
• W2510180195 cites W2094755485 @default.
• W2510180195 cites W2095023544 @default.
• W2510180195 cites W2096222053 @default.
• W2510180195 cites W2106036385 @default.
• W2510180195 cites W2110889687 @default.
• W2510180195 cites W2113596790 @default.
• W2510180195 cites W2138718114 @default.
• W2510180195 cites W2140839640 @default.
• W2510180195 cites W2144343807 @default.
• W2510180195 cites W2151189356 @default.
• W2510180195 cites W2161863791 @default.
• W2510180195 cites W2166055742 @default.
• W2510180195 cites W2167023203 @default.
• W2510180195 cites W2167854111 @default.
• W2510180195 cites W2338664084 @default.
• W2510180195 doi "https://doi.org/10.1111/jnc.13769" @default.
• W2510180195 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5118071" @default.
• W2510180195 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27513916" @default.
• W2510180195 hasPublicationYear "2016" @default.
• W2510180195 type Work @default.
• W2510180195 sameAs 2510180195 @default.
• W2510180195 citedByCount "21" @default.
• W2510180195 countsByYear W25101801952016 @default.
• W2510180195 countsByYear W25101801952017 @default.
• W2510180195 countsByYear W25101801952018 @default.
• W2510180195 countsByYear W25101801952019 @default.
• W2510180195 countsByYear W25101801952020 @default.
• W2510180195 countsByYear W25101801952021 @default.
• W2510180195 countsByYear W25101801952022 @default.
• W2510180195 countsByYear W25101801952023 @default.
• W2510180195 crossrefType "journal-article" @default.
• W2510180195 hasAuthorship W2510180195A5037853531 @default.
• W2510180195 hasAuthorship W2510180195A5051802152 @default.
• W2510180195 hasAuthorship W2510180195A5053701037 @default.
• W2510180195 hasAuthorship W2510180195A5085620061 @default.
• W2510180195 hasAuthorship W2510180195A5089659362 @default.
• W2510180195 hasBestOaLocation W25101801951 @default.
• W2510180195 hasConcept C126322002 @default.
• W2510180195 hasConcept C134018914 @default.
• W2510180195 hasConcept C137183658 @default.
• W2510180195 hasConcept C15744967 @default.
• W2510180195 hasConcept C169760540 @default.
• W2510180195 hasConcept C170493617 @default.
• W2510180195 hasConcept C185592680 @default.
• W2510180195 hasConcept C200170125 @default.
• W2510180195 hasConcept C24998067 @default.
• W2510180195 hasConcept C2775864247 @default.

• next