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- W2510188448 abstract "Recently, microRNAs (miRNA) have been proposed as regulators in the different processes involved in alcohol intake, and differences have been found in the miRNA expression profile in alcoholics. However, no study has focused on analyzing polymorphisms in genes encoding miRNAs and daily alcohol consumption at the population level. Our aim was to investigate the association between a functional polymorphism in the pre-miR-27a (rs895819 A>G) gene and alcohol consumption in an elderly population. We undertook a cross-sectional study of PREvención con DIeta MEDiterránea (PREDIMED)-Valencia participants (n = 1007, including men and women aged 67 ± 7 years) and measured their alcohol consumption (total and alcoholic beverages) through a validated questionnaire. We found a strong association between the pre-miR-27a polymorphism and total alcohol intake, this being higher in GG subjects (5.2 ± 0.4 in AA, 5.9 ± 0.5 in AG and 9.1 ± 1.8 g/day in GG; padjusted = 0.019). We also found a statistically-significant association of the pre-miR-27a polymorphism with the risk of having a high alcohol intake (>2 drinks/day in men and >1 in women): 5.9% in AA versus 17.5% in GG; padjusted < 0.001. In the sensitivity analysis, this association was homogeneous for sex, obesity and Mediterranean diet adherence. In conclusion, we report for the first time a significant association between a miRNA polymorphism (rs895819) and daily alcohol consumption." @default.
- W2510188448 created "2016-09-16" @default.
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- W2510188448 date "2016-08-16" @default.
- W2510188448 modified "2023-10-17" @default.
- W2510188448 title "MicroRNAs and Drinking: Association between the Pre-miR-27a rs895819 Polymorphism and Alcohol Consumption in a Mediterranean Population" @default.
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- W2510188448 cites W1762388503 @default.
- W2510188448 cites W1901616783 @default.
- W2510188448 cites W1910286204 @default.
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- W2510188448 cites W1963848548 @default.
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- W2510188448 cites W1977597298 @default.
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- W2510188448 cites W2018433289 @default.
- W2510188448 cites W2025184410 @default.
- W2510188448 cites W2027981586 @default.
- W2510188448 cites W2032367990 @default.
- W2510188448 cites W2038821790 @default.
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- W2510188448 doi "https://doi.org/10.3390/ijms17081338" @default.
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