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- W2510189368 abstract "Poly(γ-glutamic acid) (γ-PGA) powder was usually used as hemostatic agent because of its excellent physical properties of water-absorption and water-locking. However, if γ-PGA absorbs enough water, how about its blood compatibility? Here, the other side of the coin was investigated. The anticoagulant properties of γ-PGA were characterized by in vitro coagulation tests, hemolytic assay, platelet adhesion, and platelet activation. Moreover, cytotoxicity experiments of γ-PGA were also carried out by MTT assay. Results indicated that the sufficient water-absorbed γ-PGA has good anticoagulant property and non-cytotoxicity. It means γ-PGA has good anticoagulant property, non-cytotoxicity. If γ-PGA has absorbed enough water, it can be used as an anticoagulation biomaterial. With double effects (coagulation and anticoagulation), the γ-PGA with desirable bioproperties can be readily tailored to cater to various biomedical applications." @default.
- W2510189368 created "2016-09-16" @default.
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- W2510189368 date "2016-08-22" @default.
- W2510189368 modified "2023-10-17" @default.
- W2510189368 title "Poly(γ-glutamic acid), coagulation? Anticoagulation?" @default.
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- W2510189368 doi "https://doi.org/10.1080/09205063.2016.1221700" @default.
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