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- W2510539037 endingPage "260" @default.
- W2510539037 startingPage "247" @default.
- W2510539037 abstract "Tendon functional competence and structural integrity rely on homeostasis of tendon cell metabolism and extracellular matrix macromolecules. The clear link between tendinopathies and increasing age suggests a slow change to tendon homeostasis, which increases susceptibility to damage. Despite this well evidenced association between increasing age and tendon damage, changes to tendon mechanical properties with ageing are not clear with different studies reporting conflicting results. More recent research suggests that age-related changes occur at specific sub-structure locations and may be overlooked by measuring properties of the whole tendon. In this chapter we review changes to tendon mechanical properties, structure and composition. Mechanisms speculated to contribute to tendon change with age such as cellular senescence, ageing stem cell population, reactive oxygen species and formation of advanced glycation end-product crosslinks are discussed. Understanding age-related changes to tendon homeostasis are key to understanding increased incidence of tendon injuries in the ageing population." @default.
- W2510539037 created "2016-09-16" @default.
- W2510539037 creator A5010457913 @default.
- W2510539037 creator A5010935647 @default.
- W2510539037 creator A5014541944 @default.
- W2510539037 date "2016-01-01" @default.
- W2510539037 modified "2023-10-16" @default.
- W2510539037 title "Influence of Ageing on Tendon Homeostasis" @default.
- W2510539037 cites W1517715606 @default.
- W2510539037 cites W1603738459 @default.
- W2510539037 cites W1606658419 @default.
- W2510539037 cites W162880682 @default.
- W2510539037 cites W1829814861 @default.
- W2510539037 cites W1846157552 @default.
- W2510539037 cites W1898990224 @default.
- W2510539037 cites W1901204762 @default.
- W2510539037 cites W1950743880 @default.
- W2510539037 cites W1966843098 @default.
- W2510539037 cites W1973401962 @default.
- W2510539037 cites W1978745438 @default.
- W2510539037 cites W1980151308 @default.
- W2510539037 cites W1987316113 @default.
- W2510539037 cites W1989995073 @default.
- W2510539037 cites W1991480012 @default.
- W2510539037 cites W1994682353 @default.
- W2510539037 cites W2000020862 @default.
- W2510539037 cites W2003467384 @default.
- W2510539037 cites W2004314923 @default.
- W2510539037 cites W2007470352 @default.
- W2510539037 cites W2008010157 @default.
- W2510539037 cites W2008463780 @default.
- W2510539037 cites W2013480635 @default.
- W2510539037 cites W2022042491 @default.
- W2510539037 cites W2022341380 @default.
- W2510539037 cites W2023655454 @default.
- W2510539037 cites W2028703531 @default.
- W2510539037 cites W2032040260 @default.
- W2510539037 cites W2032263402 @default.
- W2510539037 cites W2032867856 @default.
- W2510539037 cites W2033038659 @default.
- W2510539037 cites W2033087200 @default.
- W2510539037 cites W2035487028 @default.
- W2510539037 cites W2039203709 @default.
- W2510539037 cites W2047941464 @default.
- W2510539037 cites W2048750629 @default.
- W2510539037 cites W2049446122 @default.
- W2510539037 cites W2050866825 @default.
- W2510539037 cites W2051777190 @default.
- W2510539037 cites W2052681166 @default.
- W2510539037 cites W2053173773 @default.
- W2510539037 cites W2053202302 @default.
- W2510539037 cites W2054705416 @default.
- W2510539037 cites W2056874281 @default.
- W2510539037 cites W2058222242 @default.
- W2510539037 cites W2060134459 @default.
- W2510539037 cites W2062749480 @default.
- W2510539037 cites W2066630518 @default.
- W2510539037 cites W2066915426 @default.
- W2510539037 cites W2071540582 @default.
- W2510539037 cites W2071668615 @default.
- W2510539037 cites W2071694879 @default.
- W2510539037 cites W2073552166 @default.
- W2510539037 cites W2078066502 @default.
- W2510539037 cites W2079647304 @default.
- W2510539037 cites W2080646120 @default.
- W2510539037 cites W2082402714 @default.
- W2510539037 cites W2089240903 @default.
- W2510539037 cites W2090141879 @default.
- W2510539037 cites W2102892310 @default.
- W2510539037 cites W2109296138 @default.
- W2510539037 cites W2118689023 @default.
- W2510539037 cites W2121330475 @default.
- W2510539037 cites W2123852369 @default.
- W2510539037 cites W2126525177 @default.
- W2510539037 cites W2127661946 @default.
- W2510539037 cites W2129628922 @default.
- W2510539037 cites W2131293249 @default.
- W2510539037 cites W2131774820 @default.
- W2510539037 cites W2137587164 @default.
- W2510539037 cites W2138050858 @default.
- W2510539037 cites W2143025377 @default.
- W2510539037 cites W2152791503 @default.
- W2510539037 cites W2158737938 @default.
- W2510539037 cites W2158837806 @default.
- W2510539037 cites W2158984691 @default.
- W2510539037 cites W2160734325 @default.
- W2510539037 cites W2161391346 @default.
- W2510539037 cites W2161615595 @default.
- W2510539037 cites W2163519008 @default.
- W2510539037 cites W2165549794 @default.
- W2510539037 cites W2169427827 @default.
- W2510539037 cites W2172061255 @default.
- W2510539037 cites W2315512556 @default.
- W2510539037 cites W2316811133 @default.
- W2510539037 cites W622873529 @default.
- W2510539037 doi "https://doi.org/10.1007/978-3-319-33943-6_24" @default.
- W2510539037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27535267" @default.
- W2510539037 hasPublicationYear "2016" @default.