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- W2510716823 abstract "Myeloid stem cells arising in the bone marrow can give rise to granulocytes, including neutrophils, eosinophils, basophils, and mast cells, as well as monocytes/macrophages, erythrocytes, and platelets. Stromal cells in the bone marrow create a microenvironment by the release of matrix and cytokines that determines the turnover of progenitor cells and the production of mature myeloid cells by the marrow. Human GM-CSF is a heavily glycosylated polypeptide with sizes ranging from 15,000 to 30,000 d owing to the presence of variable amounts of carbohydrate. In addition to finding differences in proliferative behavior and clonal distribution of the various cell lines, such as between fibrotic and normal lung lines or polyp and normal nasal lines, the lines for the ability to produce a variety of inflammatory, fibrogenic, or hematopoietic cytokines in vitro. Chronic respiratory tract inflammation, whether in the lung or nasal tissue, is associated with the accumulation of a variety of inflammatory cells, including monocytes, lymphocytes, neutrophils, eosinophils, mast cells." @default.
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- W2510716823 date "2022-04-19" @default.
- W2510716823 modified "2023-10-14" @default.
- W2510716823 title "Myeloid Growth Factors in the Lung" @default.
- W2510716823 doi "https://doi.org/10.1201/9781003066927-15" @default.
- W2510716823 hasPublicationYear "2022" @default.
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